Evidence map›Paper›PMID 28210099›Full record

ArticleMolecular vision2017

Study of polymorphisms in the

Edwin J Anaya-Pava, Jesús Nares-Cisneros, Rubén I Cárdenas-Hernández, Yolanda Jaramillo-Rodríguez, Graciela Zambrano-Galván

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Molecular vision, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Edwin J Anaya-PavaRetina Deparment, Instituto de la Visión, Hospital La Carlota, Montemorelos, Nuevo León, México.
Jesús Nares-CisnerosDepartment of Pediatric Gastroenterology, High Specialty Medical Unit No. 71, Mexican Institute of Social Security, Torreón, Coahuila, México.
Rubén I Cárdenas-HernándezDepartament of Ophthalmology, High Specialty Medical Unit No. 71, Mexican Institute of Social Security, Torreón, Coahuila, México.
Yolanda Jaramillo-RodríguezDepartment of General Pathology and Health Research Division, High Specialty Medical Unit No. 71, Mexican Institute of Social Security Torreón, Coahuila, México.
Graciela Zambrano-GalvánLaboratory of Molecular Stomatology, Faculty of Dentistry, Juarez University of Durango State, Durango, Durango, México.
Mexican Social Security Institute · MXInstituto de la Visión · ARUniversidad Juárez del Estado de Durango · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the frequency and association of polymorphisms in the

methodsA prospective, longitudinal, and analytical study of 11 patients diagnosed with RB was conducted. Endpoint PCR and high-resolution real-time PCR were performed. Chi-square and Student

resultsWe found a statistically significant difference between the polymorphism RB1-GG/rs9568036 and tumor chemoresistance (p<0.05). The allelic variants RB1-AA and AG/rs9568036 were determined to be associated with tumor chemosensitivity (p<0.05). A statistically significant relation between the polymorphism RB1-GG/rs9568036 and males (p = 0.0386), rate ratio (RR) = 2.0 (95% confidence interval [CI] = 0.76-5.32), as well as between the allelic variants RB1-AA and AG/rs9568036 and females (p = 0.0027), RR = 8.0 (95% CI = 1.28-50.04), was observed. We also observed a statistically significant association between the rs1042522 polymorphism in the

conclusionsThe rs9568036 polymorphism in the

Indexed as

Genetic Predisposition to DiseaseChildChild, PreschoolDNA, NeoplasmGene FrequencyHumansMexicoPolymorphism, Single NucleotideRetinoblastomaRetinoblastoma ProteinTumor Suppressor Protein p53DNA, NeoplasmRetinoblastoma ProteinTumor Suppressor Protein p53

Identifiers

PMID28210099
PMCPMC5287443
OpenAlexW2605369388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.