Evidence map›Paper›PMID 28210050›Full record

ArticleJournal of physical therapy science2017

A study of the relationships of changes in pain and gait after tourniquet-induced ischemia-reperfusion in rats.

Kazuki Aihara, Takeya Ono, Namiko Umei, Wakako Tsumiyama, Atsushi Tasaka, Hideki Ishikura, Yuta Sato, Tomohiro Matsumoto, Sadaaki Oki

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of physical therapy science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Evaluation of a simple activity measurement method in rats.Journal of physical therapy science · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Kazuki AiharaGraduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan.
Takeya OnoGraduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan; Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan.
Namiko UmeiDepartment of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan.
Wakako TsumiyamaDepartment of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan.
Atsushi TasakaDepartment of Rehabilitation Science, Osaka Health Science University, Japan.
Hideki IshikuraDepartment of Rehabilitation, Physical Therapist, Faculty of Health Sciences, Hiroshima Cosmopolitan University, Japan.
Yuta SatoGraduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan.
Tomohiro MatsumotoDepartment of Rehabilitation Science, Kobe University Graduate School of Health Science, Japan.
Sadaaki OkiGraduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan; Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan.
Prefectural University of Hiroshima · JPHiroshima Cosmopolitan University · JPKobe University · JPOsaka Health Science University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[Purpose] The purpose of this study was to determine the relationships of changes in pain and gait after ischemia reperfusion was induced by tourniquet in rats. [Subjects and Methods] The subjects were six ten-week-old male Wistar rats. Ischemia was induced in the left lower limbs of the experimental rats at a pressure of 300 mmHg for 90 minutes. Pain behavior evaluations were measured using the von Frey test in all the rats' hind limbs. A consistently increasing plantar stimulus was applied until the rats exhibited an escape behavior. For the evaluation of gait, a two-dimensional motion analysis system was used to measure the distance from the calcaneus to the floor (DCF) and toe extension angle (TEA) during gait. The evaluations were performed in the normal state, 3 hours after ischemia-reperfusion, and daily until 7 days after ischemia-reperfusion. [Results] Compared with the normal state, the means of the pain threshold showed a significant decrease until 4 days after ischemia. In addition, both TEA and DCF continued to show a significant decrease at 7 days after ischemia as compared with the normal state. [Conclusion] This study revealed that hyperalgesia occurs after ischemia-reperfusion, and recovery of hyperalgesia occurred earlier than gait dysfunction recovery.

Indexed as

GaitPainTourniquet

Identifiers

PMID28210050
PMCPMC5300816
OpenAlexW2583298485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.