Evidence map›Paper›PMID 28209971›Full record

ArticleInternational journal of obesity (2005)2017

Obesity paradox in group 1 pulmonary hypertension: analysis of the NIH-Pulmonary Hypertension registry.

S Mazimba, E Holland, V Nagarajan, A D Mihalek, J L W Kennedy, K C Bilchick

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Right ventricular function in pulmonary hypertension and obesity: a cross-sectional cohort study with survival follow-up.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Obesity Is Associated With Pulmonary Hypertension and Modifies Outcomes.Journal of the American Heart Association · 2020
    Observational
  12. Article
  13. Review
  14. Increasing the rigor of obesity research publications.International journal of obesity (2005) · 2017
    Article
  15. The 'obesity paradox' may not be a paradox at all.International journal of obesity (2005) · 2017
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S MazimbaDepartment of Medicine, University of Virginia, Charlottesville, VA, USA.
E HollandDepartment of Medicine, University of Virginia, Charlottesville, VA, USA.
V NagarajanDepartment of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
A D MihalekDepartment of Medicine, University of Virginia, Charlottesville, VA, USA.
J L W KennedyDepartment of Medicine, University of Virginia, Charlottesville, VA, USA.
K C BilchickDepartment of Medicine, University of Virginia, Charlottesville, VA, USA.

Funding

Cardiac Magnetic Resonance Imaging After Cardiac Resynchronization TherapyR03HL135463 · NHLBI · UNIVERSITY OF VIRGINIA · PI BILCHICK, KENNETH C · 2016 to 2017
$127k
NHLBI NIH HHS R03 HL135463
6 · The paper itself

Abstract

backgroundThe 'obesity paradox' refers to the fact that obese patients have better outcomes than normal weight patients. This has been observed in multiple cardiovascular conditions, but evidence for obesity paradox in pulmonary hypertension (PH) remains sparse.

methodsWe categorized 267 patients from the National Institute of Health-PH registry into five groups based on body mass index (BMI): underweight, normal weight, overweight, obese and morbidly obese. Mortality was compared in BMI groups using the χ

resultsPatients had a median age of 39 years (interquartile range 30-50 years), a median BMI of 23.4 kg m

conclusionWe observed that the best survival was in the overweight patients, making this more of an 'overweight paradox' than an 'obesity paradox'. This has implications for risk stratification and prognosis in group 1 PH patients.

Indexed as

RegistriesAdultBody Mass IndexFemaleHumansHypertension, PulmonaryIdeal Body WeightKaplan-Meier EstimateMaleMiddle AgedNational Institutes of Health (U.S.)ObesityOverweightPrognosisProportional Hazards ModelsRisk Assessment

Identifiers

PMID28209971
PMCPMC5548634

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.