Evidence map›Paper›PMID 28209808›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Galactosylation of IgA1 Is Associated with Common Variation in

Daniel P Gale, Karen Molyneux, David Wimbury, Patricia Higgins, Adam P Levine, Ben Caplin, Anna Ferlin, Peiran Yin, Christopher P Nelson, Horia Stanescu and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 4 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 4 syntheses or guidelines pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Immunosuppressive agents for treating IgA nephropathy.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Glycosylation in kidney diseases.Precision clinical medicine · 2025
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Daniel P GaleCentre for Nephrology and d.gale@ucl.ac.uk.
Karen MolyneuxDepartment of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.
David WimburyDepartment of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.
Patricia HigginsDepartment of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.
Adam P LevineDivision of Medicine, University College London, London, United Kingdom.
Ben CaplinCentre for Nephrology and.
Anna FerlinCentre for Nephrology and.
Peiran YinDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; and.
Christopher P NelsonDepartment of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Leicester, United Kingdom.
Horia StanescuCentre for Nephrology and.
Nilesh J SamaniDepartment of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Leicester, United Kingdom.
Robert KletaCentre for Nephrology and.
Xueqing YuDepartment of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; and.
Jonathan BarrattDepartment of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.
Centre for Sight · INUniversity of Leicester · GBThe First Affiliated Hospital, Sun Yat-sen University · CNNational Institute for Health Research · GBUniversity College London · GB

Funding

Medical Research Council G1002528
6 · The paper itself

Abstract

IgA nephropathy (IgAN), an important cause of kidney failure, is characterized by glomerular IgA deposition and is associated with changes in

Indexed as

FemaleGalactoseGalactosyltransferasesGenetic VariationGenome-Wide Association StudyGlomerulonephritis, IGAGlycosylationHumansImmunoglobulin AMaleC1GALT1 protein, humanGalactoseGalactosyltransferasesImmunoglobulin AGenome Wide Association Studyglomerulonephritishuman geneticsIgAIgA nephropathySNP

Identifiers

PMID28209808
PMCPMC5491291
OpenAlexW2588179969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.