Evidence map›Paper›PMID 28209736›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.

Marcin Kazmierczak, Piotr Kazmierczak, Anthony W Peng, Suzan L Harris, Prahar Shah, Jean-Luc Puel, Marc Lenoir, Santos J Franco, Martin Schwander

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 40 citations in OpenAlex.

  1. The gasdermin family: from pyroptosis mechanisms to therapeutic targets.Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Mechanistic insights into gasdermin-mediated pyroptosis.Nature reviews. Molecular cell biology · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. The Effect of aCells · 2022
    Article
  14. Article
  15. Article
  16. Signal transmission in mature mammalian vestibular hair cells.Frontiers in cellular neuroscience · 2022
    Article
  17. Gasdermins in Innate Host Defense AgainstFrontiers in immunology · 2022
    Review
  18. Review
  19. Pyroptosis, metabolism, and tumor immune microenvironment.Clinical and translational medicine · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Marcin KazmierczakDepartment of Cell Biology and Neuroscience, Rutgers the State University of New Jersey, Piscataway, New Jersey 08854.ORCID 0000-0002-4912-785X
Piotr KazmierczakInserm U1051, Institute for Neurosciences of Montpellier, 34091, Montpellier cedex 5, France.
Anthony W PengDepartment of Otolaryngology, Head and Neck Surgery, Stanford University, Stanford, California 94305.ORCID 0000-0002-2208-6779
Suzan L HarrisDepartment of Cell Biology and Neuroscience, Rutgers the State University of New Jersey, Piscataway, New Jersey 08854.
Prahar ShahDepartment of Cell Biology and Neuroscience, Rutgers the State University of New Jersey, Piscataway, New Jersey 08854.
Jean-Luc PuelInserm U1051, Institute for Neurosciences of Montpellier, 34091, Montpellier cedex 5, France.
Marc LenoirInserm U1051, Institute for Neurosciences of Montpellier, 34091, Montpellier cedex 5, France.
Santos J FrancoDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado 80045.ORCID 0000-0002-4478-5634
Martin SchwanderDepartment of Cell Biology and Neuroscience, Rutgers the State University of New Jersey, Piscataway, New Jersey 08854, schwander@biology.rutgers.edu.
Rutgers, The State University of New Jersey · USInserm · FRStanford Medicine · USUniversity of Colorado Denver · US

Funding

Tonotopic variations in mechano-electric transductionR01DC003896 · NIDCD · STANFORD UNIVERSITY · PI RICCI, ANTHONY J · 1999 to 2022
$11.1M
Mouse models to study inherited forms of deafnessR01DC007704 · NIDCD · SCRIPPS RESEARCH INSTITUTE, THE · PI MUELLER, ULRICH · 2005 to 2014
$5.0M
Physiology and Pathophysiology of Interactions between Hair Cells and Neurons.R01DC014713 · NIDCD · SCRIPPS RESEARCH INSTITUTE, THE · PI MUELLER, ULRICH · 2015 to 2019
$2.5M
The roles of gasdermins in progressive hearing lossR01DC013331 · NIDCD · RUTGERS, THE STATE UNIV OF N.J. · PI SCHWANDER, MARTIN · 2013 to 2017
$1.9M
Molecular roles in active and passive mechanics in cochlear hair bundlesR00DC013299 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI PENG, ANTHONY WEI · 2015 to 2017
$747k
Molecular roles in active and passive mechanics in cochlear hair bundlesK99DC013299 · NIDCD · STANFORD UNIVERSITY · PI PENG, ANTHONY WEI · 2013 to 2014
$248k
NIDCD NIH HHS K99 DC013299NIDCD NIH HHS R00 DC013299NIDCD NIH HHS R01 DC003896NIDCD NIH HHS R01 DC007704NIDCD NIH HHS R01 DC013331NIDCD NIH HHS R01 DC014713
6 · The paper itself

Abstract

Mutations in the

Indexed as

Mechanotransduction, CellularAnimalsCell LineGasderminsHair Cells, AuditoryHearingHearing Loss, SensorineuralMaleMiceMice, Inbred C57BLMicrofilament ProteinsMutationProteinsStereociliaGasderminsMicrofilament Proteinspejvakin protein, mouseProteinsTRIOBP protein, mouseauditory neuropathy spectrum disorderDFNB59hair cellhearing lossinner earpejvakin

Identifiers

PMID28209736
PMCPMC5373128
OpenAlexW2587913566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.