Evidence map›Paper›PMID 28209631›Full record

ArticleClinical science (London, England : 1979)2017

Human DPSCs fabricate vascularized woven bone tissue: a new tool in bone tissue engineering.

Francesca Paino, Marcella La Noce, Alessandra Giuliani, Alfredo De Rosa, Serena Mazzoni, Luigi Laino, Evzen Amler, Gianpaolo Papaccio, Vincenzo Desiderio, Virginia Tirino

Abstract readEvaluation Study
In one paragraph

Article in Clinical science (London, England : 1979), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

  1. Trial
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  5. Oscillatory fluid flow enhanced mineralization of human dental pulp cells.Frontiers in bioengineering and biotechnology · 2025
    Article
  6. Chios gum mastic enhance the proliferation and odontogenic differentiation of human dental pulp stem cells.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesca PainoDipartimento di Medicina Sperimentale, Sezione di Biotecnologie, Istologia Medica e Biologia Molecolare, Università degli Studi della Campania 'L. Vanvitelli', via L. Armanni, 5-80138, Naples, Italy.
Marcella La NoceDipartimento di Medicina Sperimentale, Sezione di Biotecnologie, Istologia Medica e Biologia Molecolare, Università degli Studi della Campania 'L. Vanvitelli', via L. Armanni, 5-80138, Naples, Italy.
Alessandra GiulianiDipartimento di Scienze Cliniche Specialistiche e Odontostomatologiche, Università Politecnica delle Marche, Via Tronto 10/a, 60020 Torrette di Ancona, Ancona, Italy.
Alfredo De RosaDipartimento Multidisciplinare Medico-chirurgico, Sezione di Odontostomatologia, Università degli Studi della Campania 'L. Vanvitelli', Via Luigi De Crecchio, 6-80138 Naples, Italy.
Serena MazzoniDipartimento di Scienze Cliniche Specialistiche e Odontostomatologiche, Università Politecnica delle Marche, Via Tronto 10/a, 60020 Torrette di Ancona, Ancona, Italy.
Luigi LainoDipartimento di Medicina Clinica e Sperimentale, Università degli Studi di Foggia, Plesso di Medicina Viale Luigi Pinto, 1-71122 Foggia, Italy.
Evzen AmlerDepartment of Biophysics, 2nd Faculty of Medicine, Charles University in Prague, V Úvalu 84, 150 06, Prague 5, Czech Republic.
Gianpaolo PapaccioDipartimento di Medicina Sperimentale, Sezione di Biotecnologie, Istologia Medica e Biologia Molecolare, Università degli Studi della Campania 'L. Vanvitelli', via L. Armanni, 5-80138, Naples, Italy.
Vincenzo DesiderioDipartimento di Medicina Sperimentale, Sezione di Biotecnologie, Istologia Medica e Biologia Molecolare, Università degli Studi della Campania 'L. Vanvitelli', via L. Armanni, 5-80138, Naples, Italy.
Virginia TirinoDipartimento di Medicina Sperimentale, Sezione di Biotecnologie, Istologia Medica e Biologia Molecolare, Università degli Studi della Campania 'L. Vanvitelli', via L. Armanni, 5-80138, Naples, Italy virginia.tirino@unina2.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human dental pulp stem cells (hDPSCs) are mesenchymal stem cells that have been successfully used in human bone tissue engineering. To establish whether these cells can lead to a bone tissue ready to be grafted, we checked DPSCs for their osteogenic and angiogenic differentiation capabilities with the specific aim of obtaining a new tool for bone transplantation. Therefore, hDPSCs were specifically selected from the stromal-vascular dental pulp fraction, using appropriate markers, and cultured. Growth curves, expression of bone-related markers, calcification and angiogenesis as well as an

Indexed as

Bone SubstitutesAdultAnimalsBone TransplantationCalcification, PhysiologicCell DifferentiationCell ProliferationCells, CulturedCell SeparationChemotaxisDental PulpHumansMice, NudeNeovascularization, PhysiologicOsteocalcinOsteogenesisBone SubstitutesOsteocalcinbone differentiationbone regenerationbone tissue engineeringhDPSCsholotomographyhuman Dental Pulp Stem Cellshuman serumphc-microCTwoven bonwoven bone

Identifiers

PMID28209631
PMCPMC5383003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.