ArticleBMC cancer2017
Papillary thyroid microcarcinoma: the significance of high risk features.
Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Clinical and pathological profile with prognostic insights in 9504 thyroid cancer cases: a single-center study (2008-2023).Journal of the Endocrine Society · 2026Article
- Papillary Thyroid Microcarcinoma: Differences between Lesions in Incidental and Nonincidental Settings-Considerations on These Clinical Entities and Personal Experience.Current oncology (Toronto, Ont.) · 2024Article
- Prognostic factors for aggressiveness in subcentimeter papillary thyroid carcinoma: impact of tumor size and lymph node metastases.Archives of endocrinology and metabolism · 2024Article
- Predictive factors and risk analysis of recurrent laryngeal nerve invasion in papillary thyroid carcinoma ≤ 1 cm.Archives of endocrinology and metabolism · 2023Article
- Thyroid Collision Tumors: The Presence of the Medullary Thyroid Carcinoma Component Negatively Influences the Prognosis.Diagnostics (Basel, Switzerland) · 2023Article
- Population-level Outcomes of Early Thyroid Cancers: A Need to Revisit Current Practice.Rambam Maimonides medical journal · 2022Article
- Differences in the clinical characteristics of papillary thyroid microcarcinoma located in the isthmus ≤5 mm and >5mm in diameter.Frontiers in oncology · 2022Article
- Systematic analysis of the lysine malonylome in Sanghuangporus sanghuang.BMC genomics · 2021Article
- Genomic and Transcriptomic Characteristics According to Size of Papillary Thyroid Microcarcinoma.Cancers · 2020Article
- Papillary thyroid microcarcinoma presenting as a metastasis to the brain.Annals of the Royal College of Surgeons of England · 2020Article
- Lymph Node Metastasis and Extrathyroidal Extension in Papillary Thyroid Microcarcinoma in Cyprus: Suspicious Subcentimeter Nodules Should Undergo FNA When Multifocality is Suspected.Journal of thyroid research · 2020Article
- Predictive Factors of Recurrence in Patients with Differentiated Thyroid Carcinoma: A Retrospective Analysis on 579 Patients.Cancers · 2019Article
- Article
- The increasing prevalence of chronic lymphocytic thyroiditis in papillary microcarcinoma.Reviews in endocrine & metabolic disorders · 2018Review
- Current Advances in Thyroid Cancer Management. Are We Ready for the Epidemic Rise of Diagnoses?International journal of molecular sciences · 2017Review
- Relationships between clinicopathological prognostic factors in papillary thyroid microcarcinoma: a refined analysis based on 428 cases.International journal of clinical and experimental pathology · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPapillary carcinomas that measure 1.0cm or less are diagnosed as papillary thyroid microcarcinomas (PTMs). The clinical significance and recommendations for management of these PTMs is still evolving. The objective of the study was to compare the characteristics of small (<5mm) to large (≥ 5mm) papillary thyroid microcarcinomas.
methodsAmongst 1459 sequential patients undergoing thyroid surgery at a single center, 132 (9%) cases were diagnosed with PTM. We performed a retrospective analysis of these cases using Fisher's Exact Test. The statistical significance was set at p < 0.05 a priori.
resultsA relationship between large PTM and high risk features was observed only for extra-thyroidal cancer extension (ETE). Six of 57 large PTM (11%) but none of the 75 small PTM had ETE (p < 0.01). Lymph node metastases were associated with both small PTM (5/9 cases) and large PTM (4/9 cases). A distant metastases was diagnosed in association with a small PTM.
conclusionsFor PTM, neither small cancer size, nor the absence of high-risk features, excluded the possibility of synchronous lymph node metastases.
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