Evidence map›Paper›PMID 28208995›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

A Comparative Analysis of Caries Inhibitory Effect of Remineralizing Agents on Human Enamel Treated With Er:YAG Laser: An In-vitro Atomic Emission Spectrometry Analysis.

Aswin Saseendran Nair, R Krishna Kumar, Sunil Thomas Philip, Syed Shaheed Ahameed, Sairaj Punnathara, Joby Peter

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aswin Saseendran NairSenior Lecturer, Department of Paedodontics, Noorul Islam College of Dental Sciences , Aralumoodu, Neyyatinkara, Trivandrum, Kerala, India .
R Krishna KumarProfessor, Department of Paedodontics and Preventive Dentistry, Rajah Muthaih Dental College and Hospital, Annamalai University , Chidambaram, Tamil Nadu, India .
Sunil Thomas PhilipProfessor, Department of Paedodontics, Noorul Islam College of Dental Sciences , Aralumoodu, Neyyatinkara, Trivandrum, Kerala, India .
Syed Shaheed AhameedSenior Lecturer, Department of Paedodontics and Preventive Dentistry, Rajah Muthaih Dental College and Hospital, Annamalai University , Chidambaram, Tamil Nadu, India .
Sairaj PunnatharaSenior Lecturer, Department of Paedodontics and Preventive Dentistry, Rajah Muthaih Dental College and Hospital, Annamalai University , Chidambaram, Tamil Nadu, India.
Joby PeterReader, Department of Paedodontics and Preventive dentistry, Rajah Muthaih Dental college and Hospital, Annamalai University , Chidambaram, Tamilnadu, India .
Noorul Islam College of Dental Science · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe tug of war to maintain tooth integrity is dependent on a ratio between demineralization and remineralization. Hence, demineralization should be retarded and remineralization should be enhanced to maintain a natural equilibrium in the oral cavity.

aimTo compare in-vitro acid resistance of human enamel when using Casein Phosphopeptides Amorphous Calcium Phosphate (CPP-ACP) [GC Tooth mousse] cream, Casein Phosphopeptide Amorphous Calcium Fluoride Phosphate (CPP-ACFP) [GC Tooth mousse plus] cream, Er:YAG laser alone, combination of CPP-ACP with Er:YAG laser, CPP-ACFP with Er:YAG laser. MATERIALS AND

methodsAn in-vitro study was done on 100 specimens which were prepared from 50 human premolars to investigate the caries inhibitory effect of remineralizing agents and laser on enamel using an atomic emission spectrometry analysis. The enamel specimens were randomly allocated into 6 groups: Untreated (control); CPP-ACP (GC Tooth mousse); CPP-ACFP (GC Tooth mousse plus); Er:YAG laser treatment alone; CPP-ACP with Er:YAG laser; CPP-ACFP with Er: YAG laser. Then specimens were immersed individually in 5ml of acetate buffer solution (0.1mol/L, pH 4.5) and incubated at 37°C for 24 hours, to determine the acid resistance by analyzing the calcium release using atomic emission spectrometry. An ANOVA model was constructed (p-value 0.05), followed by post-hoc Tukey's test for multiple pair wise comparisons of mean values.

resultsThere was a significant difference among the various groups with respect to amount of calcium released (p<0.001). The lowest mean score of calcium release was observed for CPP-ACFP with Er:YAG laser followed by CPP-ACFP but the differences between these groups were statistically not significant (p>0.05). Similarly the differences between CPP-ACP with Er:YAG laser and CPP-ACP also were not significant (p>0.05). The highest mean score of calcium release was for Er:YAG laser and no significant statistical difference was noticed in comparison with control group (p>0.05).

conclusionCombination of CPP-ACFP with Er:YAG laser is more effective in decreasing enamel demineralization when compared with other groups.

Indexed as

Acid resistanceEnamel remineralizationErbium laserTooth mousse

Identifiers

PMID28208995
PMCPMC5296568
OpenAlexW2564145772

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.