Evidence map›Paper›PMID 28208686›Full record

ArticleInternational journal of molecular sciences2017

Identification of Autophagy-Related Genes and Their Regulatory miRNAs Associated with Celiac Disease in Children.

Sergio Comincini, Federico Manai, Cristina Meazza, Sara Pagani, Carolina Martinelli, Noemi Pasqua, Gloria Pelizzo, Marco Biggiogera, Mauro Bozzola

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Moments in autophagy and disease: Past and present.Molecular aspects of medicine · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Molecular Biomarkers for Celiac Disease: Past, Present and Future.International journal of molecular sciences · 2020
    Review
  16. Review
  17. Article
  18. Autophagy and disease: unanswered questions.Cell death and differentiation · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sergio CominciniDepartment of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy. sergio.comincini@unipv.it.
Federico ManaiDepartment of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy. federico.manai01@universitadipavia.it.
Cristina MeazzaPediatrics and Adolescentology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS San Matteo, 27100 Pavia, Italy. c.meazza@smatteo.pv.it.
Sara PaganiPediatrics and Adolescentology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS San Matteo, 27100 Pavia, Italy. s.pagani@smatteo.pv.it.
Carolina MartinelliDepartment of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy. carolina.martinelli01@universitadipavia.it.
Noemi PasquaDepartment of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Fondazione IRCCS San Matteo, 27100 Pavia, Italy. noemi.pasqua@hotmail.it.
Gloria PelizzoDepartment of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Fondazione IRCCS San Matteo, 27100 Pavia, Italy. g.pelizzo@smatteo.pv.it.
Marco BiggiogeraDepartment of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy. marco.biggiogera@unipv.it.
Mauro BozzolaPediatrics and Adolescentology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS San Matteo, 27100 Pavia, Italy. mauro.bozzola@unipv.it.
University of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is a severe genetic autoimmune disorder, affecting about one in 100 people, where the ingestion of gluten leads to damage in the small intestine. Diagnosing CD is quite complex and requires blood tests and intestinal biopsy examinations. Controversy exists regarding making the diagnosis without biopsy, due to the large spectrum of manifesting symptoms; furthermore, small-intestinal gastroscopy examinations have a relatively complex management in the pediatric population. To identify novel molecular markers useful to increase the sensitivity and specificity in the diagnosis of pediatric CD patients, the expression levels of two key autophagy executor genes (

Indexed as

Gene Expression RegulationAutophagyBiomarkersBiopsyCase-Control StudiesCeliac DiseaseCell LineChildComputational BiologyFemaleGene Expression ProfilingHumansIntestinal MucosaMaleMicroRNAsModels, BiologicalBiomarkersMicroRNAsautophagyceliac disease molecular markersmicroRNA

Identifiers

PMID28208686
PMCPMC5343926
OpenAlexW2588664213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.