ArticleToxins2017
Variable Cyanobacterial Toxin and Metabolite Profiles across Six Eutrophic Lakes of Differing Physiochemical Characteristics.
Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 107 citations in OpenAlex.
- Genetic and Metabolic Diversity of Cyanobacteria on the Rock-Water Interface in Mountainous Ecosystems.Environmental science & technology · 2025Article
- Biotransformation Dynamics and Products of Cyanobacterial Secondary Metabolites in Surface Waters.Environmental science & technology · 2025Article
- Characterizing cyanopeptides and transformation products in freshwater: integrating targeted, suspect, and non-targeted analysis with in silico modeling.Analytical and bioanalytical chemistry · 2025Article
- Structure, Toxicity, Prevalence, and Degradation of Six Understudied Freshwater Cyanopeptides.Toxins · 2025Review
- Tracking Extensive Portfolio of Cyanotoxins in Five-Year Lake Survey and Identifying Indicator Metabolites of Cyanobacterial Taxa.Environmental science & technology · 2024Article
- Article
- Effects of the catastrophic 2020 Yangtze River seasonal floods on microcystins and environmental conditions in Three Gorges Reservoir Area, China.Frontiers in microbiology · 2024Article
- Expression ofApplied and environmental microbiology · 2023Article
- Metabolomics Reveals Strain-Specific Cyanopeptide Profiles and Their Production Dynamics inToxins · 2023Article
- Article
- As We Drink and Breathe: Adverse Health Effects of Microcystins and Other Harmful Algal Bloom Toxins in the Liver, Gut, Lungs and Beyond.Life (Basel, Switzerland) · 2022Review
- Article
- Preparation of Specific Nanobodies and Their Application in the Rapid Detection of Nodularin-R in Water Samples.Foods (Basel, Switzerland) · 2021Article
- Toxins and Other Bioactive Metabolites in Deep Chlorophyll Layers Containing the CyanobacteriaToxins · 2021Article
- Article
- Metabolome Variation between Strains ofToxins · 2019Article
- Cyanobacterial Toxins of the Laurentian Great Lakes, Their Toxicological Effects, and Numerical Limits in Drinking Water.Marine drugs · 2017Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Future sustainability of freshwater resources is seriously threatened due to the presence of harmful cyanobacterial blooms, and yet, the number, extent, and distribution of most cyanobacterial toxins-including "emerging" toxins and other bioactive compounds-are poorly understood. We measured 15 cyanobacterial compounds-including four microcystins (MC), saxitoxin (SXT), cylindrospermopsin (CYL), anatoxin-a (ATX) and homo-anatoxin-a (hATX), two anabaenopeptins (Apt), three cyanopeptolins (Cpt), microginin (Mgn), and nodularin (NOD)-in six freshwater lakes that regularly experience noxious cHABs. MC, a human liver toxin, was present in all six lakes and was detected in 80% of all samples. Similarly, Apt, Cpt, and Mgn were detected in all lakes in roughly 86%, 50%, and 35% of all samples, respectively. Despite being a notable brackish water toxin, NOD was detected in the two shallowest lakes-Wingra (4.3 m) and Koshkonong (2.1 m). All compounds were highly variable temporally, and spatially. Metabolite profiles were significantly different between lakes suggesting lake characteristics influenced the cyanobacterial community and/or metabolite production. Understanding how cyanobacterial toxins are distributed across eutrophic lakes may shed light onto the ecological function of these metabolites, provide valuable information for their remediation and removal, and aid in the protection of public health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.