Evidence map›Paper›PMID 28208626›Full record

ReviewGenes2017

2'-O-Methyl RNA/Ethylene-Bridged Nucleic Acid Chimera Antisense Oligonucleotides to Induce Dystrophin Exon 45 Skipping.

Tomoko Lee, Hiroyuki Awano, Mariko Yagi, Masaaki Matsumoto, Nobuaki Watanabe, Ryoya Goda, Makoto Koizumi, Yasuhiro Takeshima, Masafumi Matsuo

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Renadirsen, a Novel 2'OMeRNA/ENACurrent issues in molecular biology · 2021
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Tomoko LeeDepartment of Pediatrics, Hyogo College of Medicine, Nishinomiya 6638501, Japan. leeleetomo@me.com.
Hiroyuki AwanoDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 6500017, Japan. awahiro@med.kobe-u.ac.jp.
Mariko YagiNikoniko House Medical and Welfare Center, Kobe 6511102, Japan. marikoyagi.sgt@gmail.com.
Masaaki MatsumotoDepartment of Pediatrics, Kobe University Graduate School of Medicine, Kobe 6500017, Japan. mmatsu@med.kobe-u.ac.jp.
Nobuaki WatanabeDrug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo 1408710, Japan. watanabe.nobuaki.nc@daiichisankyo.co.jp.
Ryoya GodaDrug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo 1408710, Japan. goda.ryoya.u4@daiichisankyo.co.jp.
Makoto KoizumiModality Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo 1408710, Japan. koizumi.makoto.h7@daiichisankyo.co.jp.
Yasuhiro TakeshimaDepartment of Pediatrics, Hyogo College of Medicine, Nishinomiya 6638501, Japan. ytake@hyo-med.ac.jp.
Masafumi MatsuoDepartment of Physical Therapy, Faculty of Rehabilitation, Kobe Gakuin University, Kobe 6512180, Japan. mmatsuo@reha.kobegakuin.ac.jp.
Daiichi-Sankyo (Japan) · JPHyogo Medical University · JPKobe University · JPKobe Gakuin University · JPNikon (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a fatal muscle-wasting disease characterized by dystrophin deficiency from mutations in the

Indexed as

2′-O,4′-C-ethylene-bridged nucleic acidantisense oligonucleotideDuchenne muscular dystrophyENAexon skipping therapy

Identifiers

PMID28208626
PMCPMC5333056
OpenAlexW2589034561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.