ReviewInternational journal of environmental research and public health2017
A Review of Mercury Bioavailability in Humans and Fish.
Review in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prenatal Mercury Exposure and Neurodevelopment up to the Age of 5 Years: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Toxic Metal-Essential Trace Element Imbalance in Cardiometabolic Disease: Ferroptosis as a Mechanistic Link Between Environmental Exposure and Vascular Injury.Cardiovascular toxicology · 2026Review
- Improving mercury exposure estimates: a meta-analysis of methylmercury-to-total mercury ratios in Canadian traditional foods.Journal of exposure science & environmental epidemiology · 2026Review
- Quantifying Depuration of Methylmercury from Fish Consumption by Travelers.Environment & health (Washington, D.C.) · 2026Article
- Aligning global mercury mitigation with climate action.Nature communications · 2025Review
- A Brazilian Minamata disease? Neurologists must be aware of mercury exposure and intoxication.Arquivos de neuro-psiquiatria · 2025Review
- Exploring the Complexities of Seafood: From Benefits to Contaminants.Foods (Basel, Switzerland) · 2025Review
- Combined Effects of Arsenic, Cadmium, and Mercury with Cardiovascular Disease Risk: Insights from the All of Us Research Program.International journal of environmental research and public health · 2025Article
- Declines in anthropogenic mercury emissions in the Global North and China offset by the Global South.Nature communications · 2025Article
- Characterizing visual field loss from past mercury exposure in an Indigenous riverine community (Grassy Narrows First Nation, Canada): a cluster-based approach.Environmental health : a global access science source · 2024Article
- Tissue Distribution and Toxicological Risk Assessment of Mercury and Other Elements in Northern Populations of Wolverine (Gulo gulo).Archives of environmental contamination and toxicology · 2024Article
- An approach to assessing subsea pipeline-associated mercury release into the North Sea and its potential environmental and human health impact.Royal Society open science · 2024Article
- Article
- Some metals and metalloids in the blood of three species of shorebirds increase while foraging during two-week migratory stopover in Delaware Bay, New Jersey.Environmental research · 2023Article
- Health Benefits of Oily Fish: Illustrated with Blue Shark (Nutrients · 2023Review
- A State-of-the-Science Review on Metal Biomarkers.Current environmental health reports · 2023Review
- Metals and Metalloid Concentrations in Fish, Its Spatial Distribution in PPC, Philippines and the Attributable Risks.Toxics · 2023Article
- Intestinal bacteria diversity of suckermouth catfish (Heliyon · 2023Article
- Associations between mercury exposure with blood pressure and lipid levels: A cross-sectional study of dental professionals.Environmental research · 2023Article
- Integrating Mercury Concentrations in American Alligators (Alligator mississippiensis) with Hunter Consumption Surveys to Estimate Exposure Risk.Environmental toxicology and chemistry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To estimate human exposure to methylmercury (MeHg), risk assessors often assume 95%-100% bioavailability in their models. However, recent research suggests that assuming all, or most, of the ingested mercury (Hg) is absorbed into systemic circulation may be erroneous. The objective of this paper is to review and discuss the available state of knowledge concerning the assimilation or bioavailability of Hg in fish and humans. In fish, this meant reviewing studies on assimilation efficiency, that is the difference between ingested and excreted Hg over a given period of time. In humans, this meant reviewing studies that mostly investigated bioaccessibility (digestive processes) rather than bioavailability (cumulative digestive + absorptive processes), although studies incorporating absorption for a fuller picture of bioavailability were also included where possible. The outcome of this review shows that in a variety of organisms and experimental models that Hg bioavailability and assimilation is less than 100%. Specifically, 25 studies on fish were reviewed, and assimilation efficiencies ranged from 10% to 100% for MeHg and from 2% to 51% for Hg(II). For humans, 20 studies were reviewed with bioaccessibility estimates ranging from 2% to 100% for MeHg and 0.2% to 94% for Hg(II). The overall absorption estimates ranged from 12% to 79% for MeHg and 49% to 69% for Hg(II), and were consistently less than 100%. For both fish and humans, a number of cases are discussed in which factors (e.g., Hg source, cooking methods, nutrients) are shown to affect Hg bioavailability. The summaries presented here challenge a widely-held assumption in the Hg risk assessment field, and the paper discusses possible ways forward for the field.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.