Evidence map›Paper›PMID 28208012›Full record

ArticleBiomolecules & therapeutics2018

Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition.

Yoon Hee Chung, Keon Woong Oh, Sung Tae Kim, Eon Sub Park, Hyun Dong Je, Hyuk-Jun Yoon, Uy Dong Sohn, Ji Hoon Jeong, Hyen-Oh La

Abstract read
In one paragraph

Article in Biomolecules & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Involvement of αThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yoon Hee ChungDepartment of Anatomy, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Keon Woong OhDepartment of Pathology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Sung Tae KimDepartment of Pharmacology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Eon Sub ParkDepartment of Pathology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Hyun Dong JeDepartment of Pharmacology, College of Pharmacy, Catholic University of Daegu, Gyeongsan 38430, Republic of Korea.
Hyuk-Jun YoonDepartment of Pharmacology, College of Pharmacy, Catholic University of Daegu, Gyeongsan 38430, Republic of Korea.
Uy Dong SohnDepartment of Pharmacology, College of Pharmacy, Chung Ang University, Seoul 06974, Republic of Korea.
Ji Hoon JeongDepartment of Pharmacology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Hyen-Oh LaDepartment of Pharmacology, College of Pharmacy, The Catholic University of Korea, Bucheon 14662, Republic of Korea.
Chung-Ang University · KRCatholic University of Daegu · KRCatholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was undertaken to investigate the influence of hypothermia on endothelium-independent vascular smooth muscle contractility and to determine the mechanism underlying the relaxation. Denuded aortic rings from male rats were used and isometric contractions were recorded and combined with molecular experiments. Hypothermia significantly inhibited fluoride-, thromboxane A

Indexed as

ERK1/2fluoridehypothermiaMYPT1phorbol esterRho-kinase

Identifiers

PMID28208012
PMCPMC5839492
OpenAlexW2588005496

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.