Evidence map›Paper›PMID 28207784›Full record

ArticlePLoS genetics2017

Controlling caspase activity in life and death.

Kristin White, Eli Arama, J Marie Hardwick

Abstract readComment
In one paragraph

Article in PLoS genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Non-Apoptotic Role of Apoptotic Caspases in theFrontiers in cell and developmental biology · 2022
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kristin WhiteCutaneous Biology Research Center, Massachusetts General Hospital Research Institute/ Harvard Medical School, Boston, Massachusetts, United Sates of America.ORCID 0000-0003-0149-974X
Eli AramaDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
J Marie HardwickJohns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

Funding

Mechanisms of NeurodegenerationR01NS083373 · NINDS · JOHNS HOPKINS UNIVERSITY · PI HARDWICK, J. MARIE · 2013 to 2017
$1.8M
The regulation of cell death in vivoR01GM110477 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI WHITE, KRISTIN, ZHOU, LEI · 2015 to 2018
$1.4M
Non-apoptotic caspase activity in neuronsR21NS096677 · NINDS · JOHNS HOPKINS UNIVERSITY · PI HARDWICK, J. MARIE · 2016 to 2017
$439k
NIGMS NIH HHS R01 GM110477NIH NS092063NIH NS096677NINDS NIH HHS R01 NS083373NINDS NIH HHS R21 NS096677
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Caspase 3CaspasesApoptosisCaspase 8Cell DeathEnzyme ActivationHumansCaspase 3Caspase 8Caspases

Identifiers

PMID28207784
PMCPMC5313127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.