ArticlePLoS computational biology2017
Quantifying the Value of Perfect Information in Emergency Vaccination Campaigns.
Article in PLoS computational biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Review
- Quantifying the potential value of entomological data collection for programmatic decision-making on malaria control in sub-Saharan African settings.Malaria journal · 2025Article
- Value of information analysis for pandemic response: intensive care unit preparedness at the onset of COVID-19.BMC health services research · 2023Article
- Causes of delayed outbreak responses and their impacts on epidemic spread.Journal of the Royal Society, Interface · 2021Article
- Transient disease dynamics across ecological scales.Theoretical ecology · 2021Article
- Anticipating future learning affects current control decisions: A comparison between passive and active adaptive management in an epidemiological setting.Journal of theoretical biology · 2020Article
- Context matters: using reinforcement learning to develop human-readable, state-dependent outbreak response policies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Concurrent assessment of epidemiological and operational uncertainties for optimal outbreak control: Ebola as a case study.Proceedings. Biological sciences · 2019Article
- Quantitative impacts of incubation phase transmission of foot-and-mouth disease virus.Scientific reports · 2019Article
- Control fast or control smart: When should invading pathogens be controlled?PLoS computational biology · 2018Article
- Assessing the Economic Impact of Vaccine Availability When Controlling Foot and Mouth Disease Outbreaks.Frontiers in veterinary science · 2018Article
- Drivers of Live Cattle Price in the Livestock Trading System of Central Cameroon.Frontiers in veterinary science · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Foot-and-mouth disease outbreaks in non-endemic countries can lead to large economic costs and livestock losses but the use of vaccination has been contentious, partly due to uncertainty about emergency FMD vaccination. Value of information methods can be applied to disease outbreak problems such as FMD in order to investigate the performance improvement from resolving uncertainties. Here we calculate the expected value of resolving uncertainty about vaccine efficacy, time delay to immunity after vaccination and daily vaccination capacity for a hypothetical FMD outbreak in the UK. If it were possible to resolve all uncertainty prior to the introduction of control, we could expect savings of £55 million in outbreak cost, 221,900 livestock culled and 4.3 days of outbreak duration. All vaccination strategies were found to be preferable to a culling only strategy. However, the optimal vaccination radius was found to be highly dependent upon vaccination capacity for all management objectives. We calculate that by resolving the uncertainty surrounding vaccination capacity we would expect to return over 85% of the above savings, regardless of management objective. It may be possible to resolve uncertainty about daily vaccination capacity before an outbreak, and this would enable decision makers to select the optimal control action via careful contingency planning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.