Evidence map›Paper›PMID 28207767›Full record

ArticlePloS one2017

Osteoporosis in adult patients with atopic dermatitis: A nationwide population-based study.

Ching-Ying Wu, Ying-Yi Lu, Chun-Ching Lu, Yu-Feng Su, Tai-Hsin Tsai, Chieh-Hsin Wu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03800004 (Bone Health in Patients With Atopic Dermatitis), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03800004 completednot on this mapstarted 2018, after this paper: background citation

Bone Health in Patients With Atopic Dermatitis

TypeobservationalSponsorMayo ClinicRan2018 to 2024Enrolled30ConditionsAtopic Dermatitis, Eczema
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Generalized Pustular Psoriasis and Systemic Organ Dysfunctions.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Atopic Eczema-Associated Fracture Risk and Oral Corticosteroids: A Population-Based Cohort Study.The journal of allergy and clinical immunology. In practice · 2022
    Article
  12. Article
  13. Effector memory CD4Mucosal immunology · 2021
    Article
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Osteoporosis in Skin Diseases.International journal of molecular sciences · 2020
    Review
  19. Article
  20. Atopic eczema and fracture risk in adults: A population-based cohort study.The Journal of allergy and clinical immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ching-Ying WuDepartment of Dermatology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Ying-Yi LuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chun-Ching LuDepartment of Orthopedics, Taipei Veterans General Hospital, Taipei, Taiwan.
Yu-Feng SuDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Tai-Hsin TsaiDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chieh-Hsin WuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Kaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate osteoporosis risk in atopic dermatitis (AD) patients. This study included patients in the Taiwan National Health Insurance Research dataset. The population-based study included all patients aged 20-49 years who had been diagnosed with AD during 1996-2010. In total, 35,229 age and gender-matched patients without AD in a 1:1 ratio were randomly selected as the non-AD group. Cox proportional-hazards regression and Kaplan-Meier analyses were used to measure the hazard ratios and the cumulative incidences of osteoporosis, respectively. During the follow-up period, 360(1.02%) AD patients and 127(0.36%) non-AD patients developed osteoporosis. The overall incidence of osteoporosis was4.72-fold greater in the AD patients compared to the non-AD patients (1.82 vs. 0.24 per 1,000 person-years, respectively) after adjusting for potential confounding factors. Osteoporosis risk factors included female gender, age, advanced Charlson Comorbidity Index, depression and use of corticosteroids. The dataset analysis showed that AD was significantly associated with subsequent risk of osteoporosis.

Indexed as

Adrenal Cortex HormonesAdultAge FactorsDermatitis, AtopicFemaleHumansIncidenceKaplan-Meier EstimateMaleMiddle AgedOsteoporosisProportional Hazards ModelsRetrospective StudiesRisk FactorsSex FactorsTaiwanAdrenal Cortex Hormones

Identifiers

PMID28207767
PMCPMC5313211
OpenAlexW2588245323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.