ArticleMedicine2017
Lymphoepithelial carcinoma of the salivary glands.
Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Lymphoepithelial carcinoma of the submandibular gland in a Japanese male: A case report.Radiology case reports · 2024Article
- Intranodal palisaded myofibroblastoma in the submandibular gland region: a case report.Frontiers in oncology · 2024Article
- Epstein‑Barr virus‑associated lymphoepithelial carcinoma arising in the parotid gland: A case report and literature review.Molecular and clinical oncology · 2023Article
- Lymphoepithelial carcinoma of the oral cavity and pharynx: a SEER population-based cohort study.American journal of translational research · 2023Article
- Lymphoepithelial carcinoma of the head and neck: a SEER analysis of prognostic factors for survival.The Journal of international medical research · 2023Article
- Clinical features and treatment outcome of lymphoepithelioma-like carcinoma from multiple primary sites: a population-based, multicentre, real-world study.BMC pulmonary medicine · 2022Article
- Clinical analysis of 12 patients with primary lymphoepithelial carcinoma of the parotid gland.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Analysis of Trends in Mortality in Patients with Lymphoepithelial Carcinoma of the Head and Neck.International journal of general medicine · 2021Article
- Clinicopathological characteristics and prognostic analysis of lymphoepithelial carcinoma of salivary gland: a population-based study.Gland surgery · 2020Article
- Lymphoepithelial Carcinoma of Salivary Gland EBV-association in Endemic versus Non-Endemic Patients: A Report of 16 Cases.Head and neck pathology · 2020Article
- First Case Report of Bilateral Parotid Lymphoepithelial Carcinoma.Cancer diagnosis & prognosisArticle
- Exuberant cutaneous lymphoepithelioma-like carcinoma: clinicopathological correlation in an aggressive caseAnais brasileiros de dermatologiaArticle
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleLymphoepithelial carcinoma (LEC) is a rare malignancy with the histopathological feature of undifferentiated carcinoma and an intermixed reactive lymphoplasmacytic infiltration. Although clinically significant because of its malignant nature, it is difficult to make a differential diagnosis by preoperative imaging. Here, we report 3 cases of primary LEC arising in the major salivary glands, which showed unusual imaging features unlike other malignant tumors. PATIENT CONCERNS: Our first case is a 44-year-old man with LEC in the right parotid gland, the second case is a 71-year-old woman with LEC in the right submandibular gland, and the third case is a 35-year-old woman with LEC in the right parotid gland. All of the patients presented with a palpable mass of variable duration. DIAGNOSES: Computed tomography (CT) scans revealed a relatively well-defined, slightly hyperattenuated exophytic solid mass that had homogeneous well-enhanced regions. Ultrasonography (US) in the first 2 cases showed well-defined, hypoechoic solid masses with posterior enhancement. The CT findings seem to be benign tumors, but US features are compatible with highly cellular and hypervascular tumors.
interventionsThe resection of the involved salivary gland with postoperative radiation therapy was performed. OUTCOMES: There was no evidence of recurrence or metastasis after 5 years in all 3 patients. LESSONS: Understanding these unusual imaging findings may be helpful in detecting LEC, and may also help clinicians provide adequate management to patients, such as surgery with adjuvant radiotherapy, because of its malignant entity.
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