Evidence map›Paper›PMID 28205531›Full record

ArticleScientific reports2017

Wnt5a is a crucial regulator of neurogenesis during cerebellum development.

Chandramohan Subashini, Sivadasan Bindu Dhanesh, Chih-Ming Chen, Paul Ann Riya, Vadakkath Meera, Thulasi Sheela Divya, Rejji Kuruvilla, Kerstin Buttler, Jackson James

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  3. The meningeal-cerebellar axis: a new perspective on cerebellar development.Cellular and molecular life sciences : CMLS · 2025
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  18. Antiepileptogenic Effect of Retinoic Acid.Current neuropharmacology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Chandramohan SubashiniNeuro Stem Cell Biology Laboratory, Neurobiology Division, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala-695 014, India.
Sivadasan Bindu DhaneshNeuro Stem Cell Biology Laboratory, Neurobiology Division, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala-695 014, India.
Chih-Ming ChenDepartment of Biology, Johns Hopkins University, 3400 N. Charles St., 224 Mudd Hall, Baltimore, MD 21218, USA.
Paul Ann RiyaNeuro Stem Cell Biology Laboratory, Neurobiology Division, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala-695 014, India.
Vadakkath MeeraNeuro Stem Cell Biology Laboratory, Neurobiology Division, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala-695 014, India.
Thulasi Sheela DivyaNeuro Stem Cell Biology Laboratory, Neurobiology Division, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala-695 014, India.
Rejji KuruvillaDepartment of Biology, Johns Hopkins University, 3400 N. Charles St., 224 Mudd Hall, Baltimore, MD 21218, USA.
Kerstin ButtlerDepartment of Anatomy and Cell Biology, University Medicine Göttingen, 37075-Göttingen, Germany.
Jackson JamesNeuro Stem Cell Biology Laboratory, Neurobiology Division, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala-695 014, India.
Rajiv Gandhi Centre for Biotechnology · INJohns Hopkins University · USUniversitätsmedizin Göttingen · DE

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Neurotrophin mechanisms in neural development and diseaseR01NS073751 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KURUVILLA, REJJI · 2011 to 2015
$1.7M
NIGMS NIH HHS T32 GM007231NINDS NIH HHS R01 NS073751
6 · The paper itself

Abstract

The role of Wnt5a has been extensively explored in various aspects of development but its role in cerebellar development remains elusive. Here, for the first time we unravel the expression pattern and functional significance of Wnt5a in cerebellar development using Wnt5a

Indexed as

AnimalsBiomarkersCell ProliferationCerebellumGABAergic NeuronsGene DeletionGene ExpressionMiceMice, KnockoutMice, TransgenicMutationNeural Stem CellsNeurogenesisPurkinje CellsWnt-5a ProteinBiomarkersWnt-5a ProteinWnt5a protein, mouse

Identifiers

PMID28205531
PMCPMC5311982
OpenAlexW2588975506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.