ArticleJournal of ophthalmic inflammation and infection2017
Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS)-report 4: analysis and outcome of scleritis in an East Asian population.
Article in Journal of ophthalmic inflammation and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- JAK inhibitors in autoimmune ocular inflammatory diseases - A systematic review of case reports and series.Journal of ophthalmic inflammation and infection · 2025Review
- Rose Bengal-Assisted Photodynamic Antimicrobial Therapy for Keratitis.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2025Article
- Scleritis in Iran.Journal of ophthalmic inflammation and infection · 2025Article
- Clinical patterns and risk factors in scleritis: a multicentric study in Colombia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Necrotizing scleritis as the initial presentation of granulomatosis with polyangiitis.European journal of rheumatology · 2022Article
- Choroidal involvement in non-infectious posterior scleritis.Journal of ophthalmic inflammation and infection · 2021Review
- Monocular posterior scleritis presenting as acute conjunctivitis: A case report.World journal of clinical cases · 2020Article
- Bilateral nodular sclerokeratitis secondary to syphilis - A case report.Indian journal of ophthalmology · 2020Article
- Clinical profile of patients with anterior nodular scleritis in India.Indian journal of ophthalmology · 2020Article
- Epidemiology and Clinical Characteristics of Episcleritis and Scleritis in Olmsted County, Minnesota.American journal of ophthalmology · 2020Article
- Frequently Relapsing Anterior Nodular Scleritis as the Initial Presentation of a Lethal Systemic Infection: Disseminated Tuberculosis with HIV Coinfection.Case reports in infectious diseases · 2020Article
- Article
- Management of noninfectious scleritis.Therapeutic advances in ophthalmologyReview
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study is to evaluate the spectrum of scleritis from database of Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) at a tertiary eye referral eye institute in Singapore. Clinical records of 120 patients with scleritis from a database of 2200 patients from Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) were reviewed.
results56.6% were females, with a mean age of 48.6 ± 15.9 years. 75 (62.5%) had diffuse anterior scleritis, 25 (20.8%) had nodular anterior scleritis, 7 (5.8%) had necrotizing anterior scleritis and 13 (10.8%) had posterior scleritis. Ocular complications were observed in 53.3% of patients, including anterior uveitis (42.5%), raised intraocular pressure (12.5%), and corneal involvement (11.7%). Autoimmune causes were associated with 31 (25.8%) of patients, and 10 (8.3%) patients had an associated infective etiology, much higher than Caucasian studies. 53.3% of patients were treated with oral corticosteroids while 26.7% required immunosuppressives.
conclusionsInfective etiology needs to be considered in patients of scleritis from Asian origin. In our study and in OASIS database, scleritis was associated with systemic autoimmune disease and ocular complications.
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