SynthesisJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Negative predictive value of stress myocardial perfusion imaging and coronary computed tomography angiography: A meta-analysis.
Synthesis in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic performance of myocardial perfusion imaging with conventional and CZT single-photon emission computed tomography in detecting coronary artery disease: A meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Pooled it
- Learned high resolution energy-integrating detector CT angiography: Harnessing the power of ultra-high-resolution photon counting detector CT.Medical physics · 2025Article
- The Role of Multimodality Imaging (CT & MR) as a Guide to the Management of Chronic Coronary Syndromes.Journal of clinical medicine · 2024Review
- Development of a Non-Invasive Machine-Learned Point-of-Care Rule-Out Test for Coronary Artery Disease.Diagnostics (Basel, Switzerland) · 2024Article
- Combined evaluation of CAC score and myocardial perfusion imaging in patients at risk of cardiovascular disease: where are we and what do the data say.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Changing Paradigms in the Diagnosis of Ischemic Heart Disease by Multimodality Imaging.Journal of clinical medicine · 2022Review
- The additive prognostic value of coronary calcium score (CCS) to single photon emission computed tomography myocardial perfusion imaging (SPECT-MPI)-real world data from a single center.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Head-to-head comparison of diagnostic accuracy of stress-only myocardial perfusion imaging with conventional and cadmium-zinc telluride single-photon emission computed tomography in women with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Temporal trends of abnormal myocardial perfusion imaging in a cohort of Italian subjects: Relation with cardiovascular risk factors.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease.European journal of nuclear medicine and molecular imaging · 2020Article
- Long-term prognostic value of low-dose normal stress-only myocardial perfusion imaging by wide beam reconstruction: A competing risk analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- The machine learning approach: Artificial intelligence is coming to support critical clinical thinking.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2018. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
- Prevalence and clinical characteristics of inappropriate myocardial perfusion imaging tests at a community hospital.BMJ open quality · 2019Article
- Meta-analyses: How to critically appraise them?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Fusion of Three-Dimensional Echocardiographic Regional Myocardial Strain with Cardiac Computed Tomography for Noninvasive Evaluation of the Hemodynamic Impact of Coronary Stenosis in Patients with Chest Pain.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2018Article
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Funding
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Abstract
backgroundComparing the prognostic value of a negative finding by stress single-photon emission computed tomography myocardial perfusion imaging (MPI) and coronary computed tomography angiography (CCTA) may be useful to evaluate how better identify low-risk patients. We performed a meta-analysis to compare the long-term negative predictive value (NPV) of normal stress MPI and normal CCTA in subjects with suspected coronary artery disease (CAD). METHODS AND
resultsStudies published between January 2000 and November 2016 were identified by database search. We included MPI and CCTA studies that followed-up ≥100 subjects for ≥5 years and providing data on clinical outcome for patients with negative tests. Summary risk estimates for normal perfusion at MPI or <50% coronary stenosis at CCTA were derived in random effect regression analysis, and causes of heterogeneity were determined in meta-regression analysis. We identified 12 eligible articles (6 MPI and 6 CCTA) including 33,129 patients (26,757 in MPI and 6372 in CCTA studies) with suspected CAD. The pooled annualized event rate (AER) for occurrence of hard events (death and nonfatal myocardial infarction) was 1.06 (95% confidence interval, CI 0.49-1.64) in MPI and 0.61 (95% CI 0.35-0.86) in CCTA studies. The pooled NPV was 91% (95% CI 86-96) in MPI and 96 (95% CI 95-98) in CCTA studies. The summary rates between MPI and CCTA were not statistically different. At meta-regression analysis, no significant association between AER and clinical and demographical variables considered was found for overall studies.
conclusionsStress MPI and CCTA have a similar ability to identify low-risk patients with suspected CAD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.