Evidence map›Paper›PMID 28203777›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017

2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis.

Allan R Tunkel, Rodrigo Hasbun, Adarsh Bhimraj, Karin Byers, Sheldon L Kaplan, W Michael Scheld, Diederik van de Beek, Thomas P Bleck, Hugh J L Garton, Joseph R Zunt

3 registry-linked trialsAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 473 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
473citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06119061 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With External Ventricular Drainage

TypeinterventionalSponsorAaron CookRan2024 to 2026Enrolled20ConditionsSubarachnoid Hemorrhage, AneurysmalArmsTelavancin Injection
NCT06358209 narecruitingnot on this mapstarted 2025, after this paper: background citation

Safety and Efficacy of Ventricular Irrigation for Ventriculitis: a Randomized Controlled Trial

TypeinterventionalSponsorRenJi HospitalRan2025 to 2028Enrolled310ConditionsCentral Nervous System InfectionsArmsVentricular irrigation
NCT06650384 phase2 / phase3completednot on this mapstarted 2024, after this paper: background citation

Evaluation of the Efficacy and Safety of N-Acetylcysteine Versus Alpha-Lipoic Acid on the Occurrence and Severity of Colistin-Induced Nephrotoxicity in Critically Ill Patients

TypeinterventionalSponsorAin Shams UniversityRan2024 to 2026Enrolled180ConditionsNephrotoxicityArmsAddition of sachets of N-acetyl cysteine 1200 mg twice/day to the maintenance dose of colistin, Addition of Alpha-lipoic acid 600mg twice daily to the maintenance dose of colistin
3 · Its place in the literature

Who cites it

473 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Article
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  14. Treatment of Brain Abscess in Patient with Eisenmenger Syndrome.Journal of Korean Neurosurgical Society · 2026
    Article
  15. Methicillin-resistantJournal of surgical case reports · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Bedside external ventricular drainage in the NICU: procedural efficiency and infection trends in a 15-year single-center cohort.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  20. Observational

413 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Allan R TunkelDepartment of Internal Medicine-Infectious Diseases, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Rodrigo HasbunDepartment of Infectious Diseases, the University of Texas Health Science Center at Houston, Texas.
Adarsh BhimrajDepartment of Infectious Diseases, Cleveland Clinic, Ohio.
Karin ByersDivision of Infectious Diseases, University of Pittsburgh Medical Center, Pennsylvania.
Sheldon L KaplanDepartment of Pediatrics-Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas.
W Michael ScheldDivision of Infectious Diseases, University of Virginia, Charlottesville.
Diederik van de BeekDepartment of Neurology, Academic Medical Center, Amsterdam Neuroscience, University of Amsterdam, The Netherlands.
Thomas P BleckDepartments of Neurological Sciences, Neurosurgery, Anesthesiology, and Medicine, Rush Medical College, Chicago, Illinois.
Hugh J L GartonDepartment of Neurological Surgery, University of Michigan, Ann Arbor; and.
Joseph R ZuntDepartments of Neurology, Global Health, Medicine-Infectious Diseases, and Epidemiology, University of Washington, Seattle.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Infectious Diseases Society of America (IDSA) Standards and Practice Guidelines Committee collaborated with partner organizations to convene a panel of 10 experts on healthcare-associated ventriculitis and meningitis. The panel represented pediatric and adult specialists in the field of infectious diseases and represented other organizations whose members care for patients with healthcare-associated ventriculitis and meningitis (American Academy of Neurology, American Association of Neurological Surgeons, and Neurocritical Care Society). The panel reviewed articles based on literature reviews, review articles and book chapters, evaluated the evidence and drafted recommendations. Questions were reviewed and approved by panel members. Subcategories were included for some questions based on specific populations of patients who may develop healthcare-associated ventriculitis and meningitis after the following procedures or situations: cerebrospinal fluid shunts, cerebrospinal fluid drains, implantation of intrathecal infusion pumps, implantation of deep brain stimulation hardware, and general neurosurgery and head trauma. Recommendations were followed by the strength of the recommendation and the quality of the evidence supporting the recommendation. Many recommendations, however, were based on expert opinion because rigorous clinical data are not available. These guidelines represent a practical and useful approach to assist practicing clinicians in the management of these challenging infections.

Indexed as

central nervous system infections.cerebrospinal fluid drainscerebrospinal fluid shuntsventriculitis; meningitis

Identifiers

PMID28203777
PMCPMC5848239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.