Evidence map›Paper›PMID 28203695›Full record

Trial reportAmerican journal of hypertension2017

Does Aerobic Exercise Increase 24-Hour Ambulatory Blood Pressure Among Workers With High Occupational Physical Activity?-A RCT.

Mette Korshøj, Niklas Krause, Els Clays, Karen Søgaard, Peter Krustrup, Andreas Holtermann

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. The physical activity health paradox: what is it, why might it happen, and where to go from here?The international journal of behavioral nutrition and physical activity · 2026
    Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Mette KorshøjNational Research Centre for the Working Environment, Copenhagen, Denmark.
Niklas KrauseDepartment of Environmental Health Sciences, Fielding School of Public Health, Southern California NIOSH Education and Research Center, University of California Los Angeles, Los Angeles, US.
Els ClaysDepartment of Public Health, Ghent University, Ghent, Belgium.
Karen SøgaardDepartment of Sports Science and Clinical Biomechanics, University of Southern, Denmark, Odense, Denmark.
Peter KrustrupDepartment of Sports Science and Clinical Biomechanics, University of Southern, Denmark, Odense, Denmark.
Andreas HoltermannNational Research Centre for the Working Environment, Copenhagen, Denmark.
University of Southern Denmark · DKGhent University · BENational Research Centre for the Working Environment · DKUniversity of Copenhagen · DKUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHigh occupational physical activity (OPA) increases cardiovascular risk and aerobic exercise has been recommended for reducing this risk. This paper investigates the effects of an aerobic exercise intervention on 24-hour ambulatory blood pressure (ABP) among cleaners with high OPA.

methodsHundred and sixteen cleaners between 18 and 65 years were randomized. During the 4-month intervention period, the aerobic exercise group (AE) (n = 57) performed worksite aerobic exercise (2 × 30 minutes/week), while the reference group (REF) (n = 59) attended lectures. Between-group differences in 4-month ABP changes were evaluated by intention-to-treat analysis using a repeated-measure 2 × 2 multiadjusted mixed-models design.

resultsRelative to REF, 24-hour ABP significantly increased in AE: systolic 3.6 mm Hg (95% confidence interval (CI) 1.6-5.7) and diastolic 2.3 mm Hg (95% CI 0.9-3.8). Cleaners with high aerobic workload exhibited particularly high 24-hour ABP increases: systolic 6.0 mm Hg (95% CI 2.4-9.6), and diastolic 3.8 mm Hg (95% CI 1.3-6.4).

conclusionAerobic exercise increased 24-hour ABP among cleaners. This adverse effect raises questions about the safety and intended benefits of aerobic exercise, especially among workers with high OPA and a demanding aerobic workload. http://www.controlled-trials.com/ISRCTN86682076. Unique identifier ISRCTN86682076. CLINICAL

trial registrationTrial Number ISRCTN86682076.

Indexed as

Blood PressureExerciseHousehold WorkAdultBlood Pressure Monitoring, AmbulatoryCardiovascular DiseasesDiastoleExercise TherapyFemaleHumansMaleMiddle AgedOccupational ExposureRisk Reduction BehaviorSystoleWorkloadblood pressurecleanershypertensionobjective measurementsworksite intervention.

Identifiers

PMID28203695
PMCPMC5861546
OpenAlexW2588434282

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.