Evidence map›Paper›PMID 28203621›Full record

ArticleEuropean journal of radiology open2017

Comparative study evaluating the efficiency of cooled and uncooled single-treatment MWA in thyroid nodules after a 3-month follow up.

Oscar Maximilian Mader, Nadine Farivar Tanha, Alexander Mader, Christian Happel, Yücel Korkusuz, Frank Grünwald

Open access · goldAbstract read
In one paragraph

Article in European journal of radiology open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Oscar Maximilian MaderDepartment of Nuclear Medicine, University Hospital Frankfurt, Germany.
Nadine Farivar TanhaDepartment of Nuclear Medicine, University Hospital Frankfurt, Germany.
Alexander MaderDepartment of Nuclear Medicine, University Hospital Frankfurt, Germany.
Christian HappelDepartment of Nuclear Medicine, University Hospital Frankfurt, Germany; German Centre for Thermoablation of Thyroid Nodules, University Hospital, Frankfurt, Germany.
Yücel KorkusuzDepartment of Nuclear Medicine, University Hospital Frankfurt, Germany.
Frank GrünwaldDepartment of Nuclear Medicine, University Hospital Frankfurt, Germany; German Centre for Thermoablation of Thyroid Nodules, University Hospital, Frankfurt, Germany.
University Hospital Frankfurt · DEGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate and compare the efficacy of single-treatment cooled and uncooled microwave ablation in thyroid nodules.

methodsEighteen patients (11 women) with an average age of 62 years (range: 41-80) with 18 cold, mainly solid or solid thyroid nodules were treated with cooled or uncooled microwave ablation. Pain during the treatment was measured on a 10-point score. Side effects revealed by ultrasound or patients' complaints were documented. Laboratory data was evaluated before, 24 h and three months after MWA. Nodule volumes were measured before and three months after MWA.

resultsCooled MWA was better tolerated than uncooled MWA. A significant reduction of thyroid nodule volume was observed in all cases. The reduction after cMWA was higher (40%) than after uMWA (29%). Pain intensity during cMWA was significantly lower than after uMWA. CMWA and uMWA led to a significant decrease of nodule blood circulation and echogenicity and to a significant increase of nodule elasticity. Thyroid function remained intact in all cases. The energy (kJ/s) administered into the nodules in relation to the ablation time during cMWA was higher than during uMWA.

conclusionsCMWA leads to a slightly higher but statistically not significant nodule volume reduction than uMWA. Patient comfort during cMWA is higher than during uMWA. The risk of unintended side effects is less in cMWA. A Single-treatment provides sufficient results.

Indexed as

cMWA, cooled microwave ablationIC, internally cooled shaft antennaMicrowave ablationMWA, microwave ablatioNIC, non-internallyPain scale MWAPEIT, Percutaneous ethanol injectionRFA, radiofrequency ablationRIT, radioiodine therapy cooled shaft antennaSingle-treatmentuMWA, uncooled microwave ablationUS, ultrasoundVolume reduction of thyroid nodules

Identifiers

PMID28203621
PMCPMC5295504
OpenAlexW2583665818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.