Evidence map›Paper›PMID 28203484›Full record

ArticleAging and disease2017

LW-AFC Effects on

Jianhui Wang, Xiaorui Cheng, Ju Zeng, Jiangbei Yuan, Zhongfu Wang, Wenxia Zhou, Yongxiang Zhang

Open access · goldAbstract read
In one paragraph

Article in Aging and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jianhui Wang1Department of TCM and Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China; 2State Key Laboratory of Toxicology and Medical Countermeasures, Beijing 100850, China.
Xiaorui Cheng1Department of TCM and Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China; 2State Key Laboratory of Toxicology and Medical Countermeasures, Beijing 100850, China.
Ju Zeng1Department of TCM and Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China; 2State Key Laboratory of Toxicology and Medical Countermeasures, Beijing 100850, China.
Jiangbei Yuan3Educational Ministry Key Laboratory of Resource Biology and Biotechnology in Western China, Life Sciences College, Northwest University, Xi'an 710069, China.
Zhongfu Wang3Educational Ministry Key Laboratory of Resource Biology and Biotechnology in Western China, Life Sciences College, Northwest University, Xi'an 710069, China.
Wenxia Zhou1Department of TCM and Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China; 2State Key Laboratory of Toxicology and Medical Countermeasures, Beijing 100850, China.
Yongxiang Zhang1Department of TCM and Neuroimmunopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China; 2State Key Laboratory of Toxicology and Medical Countermeasures, Beijing 100850, China.
Institute of Pharmacology · CZMinistry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycosylation is one of the most common eukaryotic post-translational modifications, and aberrant glycosylation has been linked to many diseases. However, glycosylation and glycome analysis is a significantly challenging task. Although several lines of evidence have indicated that protein glycosylation is defective in Alzheimer's disease (AD), only a few studies have focused on AD glycomics. The etiology of AD is unclear and there are no effective disease-modifying treatments for AD. In this study, we found that the object recognition memory, passive avoidance, and spatial learning and memory of senescence-accelerated mouse prone 8 (SAMP8) strain, an AD animal model, were deficient, and LW-AFC, which was prepared from the traditional Chinese medicine prescription Liuwei Dihuang decoction, showed beneficial effects on the deterioration of cognitive capability in SAMP8 mice. Forty-three and 56

Indexed as

Alzheimer’s diseaseglycomeLW-AFCsenescence-accelerated mouse prone 8 straintraditional Chinese medicine

Identifiers

PMID28203484
PMCPMC5287383
OpenAlexW2584298660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.