Evidence map›Paper›PMID 28203483›Full record

ArticleAging and disease2017

Galanin Protects from Caspase-8/12-initiated Neuronal Apoptosis in the Ischemic Mouse Brain via GalR1.

Yun Li, Zhu Mei, Shuiqiao Liu, Tong Wang, Hui Li, Xiao-Xiao Li, Song Han, Yutao Yang, Junfa Li, Zhi-Qing David Xu

Open access · goldAbstract read
In one paragraph

Article in Aging and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Activation of Galanin Receptor 1 with M617 Attenuates Neuronal Apoptosis via ERK/GSK-3β/TIP60 Pathway After Subarachnoid Hemorrhage in Rats.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Article
  4. An assembly of galanin-galanin receptor signaling network.Journal of cell communication and signaling · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yun LiDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Zhu MeiDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Shuiqiao LiuDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Tong WangDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Hui LiDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Xiao-Xiao LiDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Song HanDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Yutao YangDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Junfa LiDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Zhi-Qing David XuDepartment of Neurobiology and Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.
Chinese Institute for Brain Research · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Galanin (GAL) plays key role in many pathophysiological processes, but its role in ischemic stroke remains unclear. Here, the models of 1 h middle cerebral artery occlusion (MCAO)/1-7 d reperfusion (R)-induced ischemic stroke and

Indexed as

ApoptosisNeuroprotectionNeurotransmittersReceptorsStroke

Identifiers

PMID28203483
PMCPMC5287390
OpenAlexW2585778820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.