ArticleJournal of thoracic disease2017
Relationship between radiologic patterns, pulmonary function values and bronchoalveolar lavage fluid cells in newly diagnosed sarcoidosis.
Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Evaluation of Delphi high-resolution computed tomography phenotype classification for treatment-naïve patients with pulmonary sarcoidosis.Quantitative imaging in medicine and surgery · 2026Article
- Morphological computed tomography phenotypes in pulmonary sarcoidosis at diagnosis: splitting and lumping based on predictors of clinical progression.ERJ open research · 2026Article
- Evaluation of squamous cell carcinoma antigen as a diagnostic biomarker in pulmonary diseases: a male cohort study.Diagnostic pathology · 2026Article
- Scoping out sarcoidosis: the evolving role of bronchoscopy.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Integrated Bioinformatics Methods Were Employed to Investigate Potential Molecular Links Between Obstructive Sleep Apnea and Sarcoidosis.Mediators of inflammation · 2026Article
- Tobacco smoking and sarcoidosis revisited-Evidence, mechanisms, and clinical implications: a narrative review.Current medical research and opinion · 2025Review
- Fibrotic Pulmonary Sarcoidosis-From Pathogenesis to Management.Journal of clinical medicine · 2025Review
- Radiological phenotypes in pulmonary sarcoidosis: a reliability study of newly defined high-resolution computer tomography phenotypes.BJR open · 2025Article
- Relationship Between Thoracic CT Severity Score and Scadding Staging With PFT, DLCO, and 6MWT in Patients With Sarcoidosis.Canadian respiratory journal · 2025Article
- Phenotyping sarcoidosis: a single institution retrospective analysis.Frontiers in medicine · 2025Article
- Article
- Phenotypes and Serum Biomarkers in Sarcoidosis.Diagnostics (Basel, Switzerland) · 2024Review
- Pulmonary Function in Pulmonary Sarcoidosis.Journal of clinical medicine · 2023Review
- Lymphocyte Subsets and Pulmonary Nodules to Predict the Progression of Sarcoidosis.Biomedicines · 2023Article
- Pulmonary Sarcoidosis: Beyond Restriction and Forced Vital Capacity.Annals of the American Thoracic Society · 2023Article
- Heterogeneity of Lung Function Phenotypes in Sarcoidosis: Role of Race and Sex Differences.Annals of the American Thoracic Society · 2023Article
- Frequency of peripheral blood eosinophilia and obstructive airway disease in sarcoidosis.Turkish journal of medical sciences · 2021Article
- CD31Journal of thoracic disease · 2021Article
- Neutrophils in Bronchoalveolar Lavage Fluid Indicating the Severity and Relapse of Pulmonary Sarcoidosis.Frontiers in medicine · 2021Article
- Hydrogen sulfide alleviates cigarette smoke-induced COPD through inhibition of the TGF-Experimental biology and medicine (Maywood, N.J.) · 2020Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the present study was to identify specious radiologic and/or physiologic prognostic marker(s), which lead to optimize of the patient follow-up frequency.
methodsEighty consecutive patients with newly diagnosed pulmonary sarcoidosis. Patients underwent chest radiography, high-resolution computed tomography (HRCT) examination, pulmonary function tests (PFT), bronchoscopy with bronchoalveolar lavage (BAL) and lung biopsy, and bronchoalveolar lavage fluid (BALF) cell examination.
resultsThe reduction in PFT values seen in radiological sarcoidosis stage III was greater than that seen in stages I and II. The percentage of neutrophils in the lungs was found to increase in stages II and III. PFT indices were correlated negatively with the consolidation and ground glass opacities CT scores, but not with the micronodule or macronodule scores. The rise in the percentage of BALF lymphocytes was associated with the restriction pattern of PFT. The diagnostic value of BALF for sarcoidosis was higher when the typical radiologic patterns of stage I disease were found and that smoking decreased the diagnostic value of CD4/CD8 ratio.
conclusionsThis study supports the opinion that the staging of the pulmonary sarcoidosis with chest X-rays is still valuable from the prognostic point of view, because significant correlations between the radiologic stages of sarcoidosis and PFT parameters were found. Chest HRCT was significantly superior to chest X-ray in detecting mediastinal and pulmonary parenchymal changes. However, the prognostic role of HRCT needs to be better investigated evaluating serial examinations. Only consolidation and ground glass scores (neither of which are frequently found in sarcoidosis) hold prognostic value, since these were negatively correlated with PFT parameters.
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