Evidence map›Paper›PMID 28203390›Full record

ReviewInterventional medicine & applied science2016

Soluble vascular cell adhesion molecule-1 and magnesium sulfate with nifedipine treatment in Indonesian women with severe pre-eclampsia.

Hotma Partogi Pasaribu, Herman Hariman, R Haryono Roeshadi, Stephen C L Koh

Open access · diamondAbstract readReview
In one paragraph

Review in Interventional medicine & applied science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hotma Partogi PasaribuDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sumatera Utara , Medan, Indonesia.
Herman HarimanDepartment of Clinical Pathology, Faculty of Medicine, Universitas Sumatera Utara , Medan, Indonesia.
R Haryono RoeshadiDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sumatera Utara , Medan, Indonesia.
Stephen C L KohDepartment of Clinical Pathology, Faculty of Medicine, Universitas Sumatera Utara , Medan, Indonesia.
University of North Sumatra · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndothelial cell activation in pre-eclampsia is associated with elevated soluble vascular cell adhesion molecule-1 (sVCAM-1) levels. The objective of the study was to determine whether sVCAM-1 levels in Indonesian women with pre-eclampsia were similar to other ethnic studies and to determine the effects of magnesium sulfate with nifedipine on blood pressure.

methodsA total of 61 pregnant women were admitted, who had normal pregnancy (

resultsThe mean ages in normal pregnancy (

conclusionElevated sVCAM-1 levels were also seen in Indonesian women with severe pre-eclampsia. The placenta may not be the only source of elevated sVCAM-1 and that endothelial dysfunction persists beyond the postpartum period. Magnesium sulfate together with nifedipine significantly lowered blood pressure. The determination of elevated sVCAM-1 in pregnancy as a risk marker for endothelial dysfunction is therefore suggested.

Indexed as

blood pressuremagnesium sulfatenifedipinenormal pregnancypre-eclampsiasVCAM-1

Identifiers

PMID28203390
PMCPMC5283762
OpenAlexW2528457375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.