ArticleIranian journal of pediatrics2016
The Relationship of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio with Gastrointestinal Bleeding in Henoch-Schonlein Purpura.
Article in Iranian journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Clinical relevance of neutrophil-to-lymphocyte ratio and mean platelet volume in pediatric Henoch-Schonlein Purpura: a meta-analysis.Bioengineered · 2021Pooled it
- Development and validation of a clinical prediction model for gastrointestinal hemorrhage in pediatric IgA vasculitis.BMC pediatrics · 2026Observational
- A predictive model based on routine blood inflammatory markers for IgA vasculitis in children.Frontiers in pediatrics · 2026Article
- Predictive Laboratory Markers for Gastrointestinal Complications in Children with Henoch-Schönlein Purpura.Journal of multidisciplinary healthcare · 2025Article
- Analysis of the influencing factors of abdominal Henoch-Schonlein purpura in children with gastrointestinal bleeding and the clinical value of PLR.American journal of translational research · 2024Article
- Immunological Features of Children with Gastrointestinal Bleeding Due to Henoch-Schönlein Purpura.Pediatric health, medicine and therapeutics · 2024Article
- Severe gastrointestinal involvement in pediatric IgA vasculitis: a retrospective single-center cohort study in China.Frontiers in pediatrics · 2023Article
- Association between common laboratory indices and IgAV recurrence in children.BMC pediatrics · 2022Article
- Analysis of children with Henoch-Schonlein purpura secondary to infection.Clinical rheumatology · 2022Article
- Construction and internal validation of a predictive model for risk of gastrointestinal bleeding in children with abdominal Henoch-Schönlein purpura: A single-center retrospective case-control study.Frontiers in immunology · 2022Article
- Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Pediatric Acute Respiratory Distress Syndrome.Turkish thoracic journal · 2021Article
- Multisystemic manifestations of IgA vasculitis.Clinical rheumatology · 2021Review
- Predictive Value of Laboratory Indexes on Renal Involvement in Children with Henoch-Schönlein Purpura.International journal of general medicine · 2021Article
- Immature Granulocyte Count and Percentage as New Predictors of Mortality in Patients with Upper Gastrointestinal Bleeding.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020Article
- Serologic and Histologic Predictors of Long-Term Renal Outcome in Biopsy-Confirmed IgA Nephropathy (Haas Classification): An Observational Study.Journal of clinical medicine · 2019Article
- Analysis of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio and mean platelet volume to platelet count ratio in children with acute stage of immunoglobulin A vasculitis and assessment of their suitability for predicting the course of the disease.Rheumatology international · 2019Article
- Insight into inflammatory cell and cytokine profiles in adult IgA vasculitis.Clinical rheumatology · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesHenoch-Schonlein Purpura (HSP) is the most widespread systemic vasculitis during childhood. Gastrointestinal tract retention and gastrointestinal bleeding are among its major complications. Neutrophil-Lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are indicators related to inflammatory diseases. This study evaluated the relationship between NLR or PLR and gastrointestinal bleeding in HSP.
methodsThe study consisted of 119 patients and 40 healthy children in the same age group. White Blood Cell (WBC) count, hemoglobin level, platelet count, mean platelet volume (MPV), neutrophil count and lymphocyte count were recorded. The NLR and PLR were calculated based on the results of complete blood count tests performed during the first visit to the hospital.
resultsThe average neutrophil count and NLR of the patients with HSP were found to be significantly increased compared to the control group (P = 0.0001). No significant difference was observed between the PLR average of HSP and control groups (P = 0.053). Platelet count average (P = 0.0001) and PLR (P = 0.001) of the patients with gastrointestinal system (GIS) bleeding were found to be statistically significantly increased compared to those who did not have gastrointestinal bleeding. No significant difference was found in the NLR of the patients with and without gastrointestinal bleeding (P = 0.060).
conclusionsWhile the NLR was significantly increased in patients with HSP in this study, the PLR was found to be more significant in patients with gastrointestinal bleeding. Similar to NLR, PLR may also be used as an inflammatory indicator among children with HSP, who have gastrointestinal bleeding.
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