Evidence map›Paper›PMID 28203206›Full record

ArticleFrontiers in physiology2017

Mild and Short-Term Caloric Restriction Prevents Obesity-Induced Cardiomyopathy in Young Zucker Rats without Changing in Metabolites and Fatty Acids Cardiac Profile.

Gema Ruiz-Hurtado, Concha F García-Prieto, Helena Pulido-Olmo, Juan P Velasco-Martín, Palmira Villa-Valverde, María E Fernández-Valle, Lisardo Boscá, María Fernández-Velasco, Javier Regadera, Beatriz Somoza and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 29 citations in OpenAlex.

  1. Astrocytic CaGlia · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Gema Ruiz-HurtadoUnidad de Hipertensión, Instituto de Investigación Imas12, Hospital Universitario 12 de OctubreMadrid, Spain; Facultad de Farmacia, Instituto Pluridisciplinar, Universidad Complutense de MadridMadrid, Spain.
Concha F García-PrietoDepartamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad CEU-San Pablo Madrid, Spain.
Helena Pulido-OlmoUnidad de Hipertensión, Instituto de Investigación Imas12, Hospital Universitario 12 de OctubreMadrid, Spain; Facultad de Farmacia, Instituto Pluridisciplinar, Universidad Complutense de MadridMadrid, Spain.
Juan P Velasco-MartínDepartamento de Anatomía, Histología y Neurociencia, Facultad de Medicina. Universidad Autónoma de Madrid Madrid, Spain.
Palmira Villa-ValverdeCAI de RMN y RSE, Facultad de Químicas, Universidad Complutense Madrid, Spain.
María E Fernández-ValleCAI de RMN y RSE, Facultad de Químicas, Universidad Complutense Madrid, Spain.
Lisardo BoscáDepartamento de Metabolismo y Señalización Celular, Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) Madrid, Spain.
María Fernández-VelascoDepartamento de Metabolismo y Señalización Celular, Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM)Madrid, Spain; Departamento de Metabolismo y Señalización Celular, Instituto de Investigación Hospital Universitario La Paz (IdiPAZ)Madrid, Spain.
Javier RegaderaDepartamento de Anatomía, Histología y Neurociencia, Facultad de Medicina. Universidad Autónoma de Madrid Madrid, Spain.
Beatriz SomozaDepartamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad CEU-San Pablo Madrid, Spain.
María S Fernández-AlfonsoFacultad de Farmacia, Instituto Pluridisciplinar, Universidad Complutense de Madrid Madrid, Spain.
Universidad Autónoma de Madrid · ESUniversidad Complutense de Madrid · ESHospital Universitario 12 De Octubre · ESUniversidad San Pablo CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caloric restriction (CR) ameliorates cardiac dysfunction associated with obesity. However, most of the studies have been performed under severe CR (30-65% caloric intake decrease) for several months or even years in aged animals. Here, we investigated whether mild (20% food intake reduction) and short-term (2-weeks) CR prevented the obese cardiomyopathy phenotype and improved the metabolic profile of young (14 weeks of age) genetically obese Zucker

Indexed as

caloric restrictionhypertensionhypertrophymetabolite profilenuclear magnetic resonanceobesity-induced cardiomyopathy

Identifiers

PMID28203206
PMCPMC5285365
OpenAlexW2583263865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.