Evidence map›Paper›PMID 28203204›Full record

ReviewFrontiers in pharmacology2017

Circulating Tumor Cells: From Theory to Nanotechnology-Based Detection.

Yue Ming, Yuanyuan Li, Haiyan Xing, Minghe Luo, Ziwei Li, Jianhong Chen, Jingxin Mo, Sanjun Shi

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yue MingDepartment of Pharmacy, Institute of Surgery Research, Daping Hospital, Third Military Medical University Chongqing, China.
Yuanyuan LiDepartment of Pharmacy, Institute of Surgery Research, Daping Hospital, Third Military Medical University Chongqing, China.
Haiyan XingDepartment of Pharmacy, Institute of Surgery Research, Daping Hospital, Third Military Medical University Chongqing, China.
Minghe LuoDepartment of Pharmacy, Institute of Surgery Research, Daping Hospital, Third Military Medical University Chongqing, China.
Ziwei LiDepartment of Pharmacy, Institute of Surgery Research, Daping Hospital, Third Military Medical University Chongqing, China.
Jianhong ChenDepartment of Pharmacy, Institute of Surgery Research, Daping Hospital, Third Military Medical University Chongqing, China.
Jingxin MoKey Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen UniversityGuangzhou, China; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen UniversityGuangzhou, China.
Sanjun ShiDepartment of Pharmacy, Institute of Surgery Research, Daping Hospital, Third Military Medical University Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells with stem-cell properties are regarded as tumor initiating cells. Sharing stem-cell properties, circulating tumor cells (CTCs) are responsible for the development of metastasis, which significant affects CTC analysis in clinical practice. Due to their extremely low occurrence in blood, however, it is challenging to enumerate and analyze CTCs. Nanotechnology is able to address the problems of insufficient capture efficiency and low purity of CTCs owing to the unique structural and functional properties of nanomaterials, showing strong promise for CTC isolation and detection. In this review, we discuss the role of stem-like CTCs in metastases, provide insight into recent progress in CTC isolation and detection approaches using various nanoplatforms, and highlight the role of nanotechnology in the advancement of CTC research.

Indexed as

cancer stem cellscirculating tumor cellsCTC isolation and detectionmetastasisnanotechnologystem-cell properties

Identifiers

PMID28203204
PMCPMC5285331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.