Evidence map›Paper›PMID 28203071›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2017

Long-acting bronchodilators with or without inhaled corticosteroids and 30-day readmission in patients hospitalized for COPD.

Raju Bishwakarma, Wei Zhang, Yong-Fang Kuo, Gulshan Sharma

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. International journal of chronic obstructive pulmonary disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raju BishwakarmaDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine.
Wei ZhangDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine.
Yong-Fang KuoOffice of Biostatistics; Sealy Center of Aging, University of Texas Medical Branch, Galveston, TX, USA.
Gulshan SharmaDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine; Sealy Center of Aging, University of Texas Medical Branch, Galveston, TX, USA.

Funding

UTMB Clinical and Translational Science AwardUL1TR001439 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI URBAN, RANDALL J · 2015 to 2024
$40.0M
UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
Assessing The Role of Nurse Practitioner in Primary Care of Older AdultsR01HS020642 · AHRQ · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KUO, YONG-FANG · 2012 to 2019
$1.4M
AHRQ HHS R01 HS020642AHRQ HHS R24 HS022134NCATS NIH HHS UL1 TR001439NIA NIH HHS P30 AG024832
6 · The paper itself

Abstract

backgroundThe ability of a long-acting muscarinic antagonist (LAMA) and long-acting beta 2 agonists (LABAs; long-acting bronchodilators, LABDs) with or without inhaled corticosteroids (ICSs) to reduce early readmission in hospitalized patients with COPD is unknown.

methodsWe studied a 5% sample of Medicare beneficiaries enrolled in Medicare parts A, B and D and hospitalized for COPD in 2011. We examined prescriptions filled for LABDs with or without ICSs (LABDs±ICSs) within 90 days prior to and 30 days after hospitalization. Primary outcome was the 30-day readmission rate between "users" and "nonusers" of LABDs±ICSs. Propensity score matching and sensitivity analysis were performed by limiting analysis to patients hospitalized for acute exacerbation of COPD (AECOPD). Among 6,066 patients hospitalized for COPD, 3,747 (61.8%) used LABDs±ICSs during the specified period. The "user" and "nonuser" groups had similar rates of all-cause emergency room (ER) visits and readmissions within 30 days of discharge date (22.4% vs 20.7%,

conclusionUse of LABDs±ICSs did not reduce 30-day readmissions in patients hospitalized for COPD.

Indexed as

Patient ReadmissionAdministration, InhalationAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAgedAged, 80 and overBronchodilator AgentsChi-Square DistributionDisease ProgressionDrug PrescriptionsEmergency Service, HospitalFemaleHumansLogistic ModelsLungMaleAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsBronchodilator AgentsMuscarinic AntagonistsCOPDlong-acting bronchodilatorsMedicarereadmission

Identifiers

PMID28203071
PMCPMC5293361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.