ArticleInternal medicine (Tokyo, Japan)2017
Clinical Presentation of Tubulointerstitial Nephritis Caused by Amyloid Light-chain Amyloidosis in a Patient with Sjögren's Syndrome.
Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Localized Nodular Amyloidosis of the Buccal Mucosa Associated with Sjögren's Syndrome: A Case Report and Literature Review.Yonago acta medica · 2025Article
- Primary Localized Labial Amyloidosis Associated with Sjögren Syndrome.Head and neck pathology · 2024Article
- Tubular basement membrane amyloid deposition: is it an indicator of renal progression in light chain amyloidosis?Renal failure · 2023Article
- Pulmonary amyloidosis and cystic lung disease in primary Sjögren's syndrome: a case report and literature review.Clinical rheumatology · 2021Review
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Authors and funding
10 authors.
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Abstract
We report a 70-year-old woman with Sjögren's syndrome who had severe renal dysfunction with mild proteinuria and elevated urinary low-molecular-weight proteins. Based on these clinical presentations, interstitial nephritis due to Sjögren's syndrome was strongly suspected. Unexpectedly, renal pathology revealed amyloid light-chain (AL) lambda-type depositions predominantly in the vasculatures with severe tubulointerstitial damage. Concentrated urine immunofixation was positive for Bence Jones lambda-type monoclonal proteins. Given the involvement in other organs, systemic AL amyloidosis was diagnosed. The patient underwent chemotherapy, but hemodialysis was ultimately instituted. It should be remembered that renal amyloidosis occurs as a clinical presentation of interstitial nephritis.
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