Evidence map›Paper›PMID 28202755›Full record

ArticleJournal of virology2017

Low-Pathogenic Influenza A Viruses in North American Diving Ducks Contribute to the Emergence of a Novel Highly Pathogenic Influenza A(H7N8) Virus.

Yifei Xu, Andrew M Ramey, Andrew S Bowman, Thomas J DeLiberto, Mary L Killian, Scott Krauss, Jacqueline M Nolting, Mia Kim Torchetti, Andrew B Reeves, Richard J Webby and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

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  7. Continental-scale dynamics of avian influenza in U.S. waterfowl are driven by demography, migration, and temperature.Ecological applications : a publication of the Ecological Society of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Yifei XuDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA.
Andrew M RameyU.S. Geological Survey, Alaska Science Center, Anchorage, Alaska, USA aramey@usgs.gov wan@cvm.msstate.edu.
Andrew S BowmanDepartment of Veterinary Preventive Medicine, Ohio State University, Columbus, Ohio, USA.
Thomas J DeLibertoNational Wildlife Disease Program, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado, USA.
Mary L KillianNational Veterinary Services Laboratories, Veterinary Services, U.S. Department of Agriculture, Ames, Iowa, USA.
Scott KraussDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Jacqueline M NoltingDepartment of Veterinary Preventive Medicine, Ohio State University, Columbus, Ohio, USA.
Mia Kim TorchettiNational Veterinary Services Laboratories, Veterinary Services, U.S. Department of Agriculture, Ames, Iowa, USA.
Andrew B ReevesU.S. Geological Survey, Alaska Science Center, Anchorage, Alaska, USA.
Richard J WebbyDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
David E StallknechtSoutheastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
Xiu-Feng WanDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA aramey@usgs.gov wan@cvm.msstate.edu.
Mississippi State University · USSt. Jude Children's Research Hospital · USThe Ohio State University · USAnimal and Plant Health Inspection Service · USUnited States Geological Survey · USUniversity of Georgia · USU.S. Geological Survey, Alaska Science Center

Funding

Zinc dependent conformational changes in AdcR and their impact on DNA bindingP20GM103646 · NIGMS · MISSISSIPPI STATE UNIVERSITY · PI THIBAUDEAU, GISELLE · 2013 to 2022
$21.1M
NIAID NIH HHS HHSN272201400006CNIGMS NIH HHS P20 GM103646
6 · The paper itself

Abstract

Introductions of low-pathogenic avian influenza (LPAI) viruses of subtypes H5 and H7 into poultry from wild birds have the potential to mutate to highly pathogenic avian influenza (HPAI) viruses, but such viruses' origins are often unclear. In January 2016, a novel H7N8 HPAI virus caused an outbreak in turkeys in Indiana, USA. To determine the virus's origin, we sequenced the genomes of 441 wild-bird origin influenza A viruses (IAVs) from North America and subjected them to evolutionary analyses. The results showed that the H7N8 LPAI virus most likely circulated among diving ducks in the Mississippi flyway during autumn 2015 and was subsequently introduced to Indiana turkeys, in which it evolved high pathogenicity. Preceding the outbreak, an isolate with six gene segments (PB2, PB1, PA, HA, NA, and NS) sharing >99% sequence identity with those of H7N8 turkey isolates was recovered from a diving duck sampled in Kentucky, USA. H4N8 IAVs from other diving ducks possessed five H7N8-like gene segments (PB2, PB1, NA, MP, and NS; >98% sequence identity). Our findings suggest that viral gene constellations circulating among diving ducks can contribute to the emergence of IAVs that affect poultry. Therefore, diving ducks may serve an important and understudied role in the maintenance, diversification, and transmission of IAVs in the wild-bird reservoir.

Indexed as

AnimalsAnimals, WildBase SequenceDisease OutbreaksDucksEvolution, MolecularGenome, ViralInfluenza A virusInfluenza in BirdsPhylogenyPoultry DiseasesRecombination, GeneticSequence Analysis, RNATurkeysdiving duckevolutionary networkgenetic reassortmenthighly pathogenic avian influenzalow-pathogenic avian influenzasubtype H7N8wild birds

Identifiers

PMID28202755
PMCPMC5391441
OpenAlexW2588108748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.