Evidence map›Paper›PMID 28202733›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Specificity of genome evolution in experimental populations of

Daniel E Deatherage, Jamie L Kepner, Albert F Bennett, Richard E Lenski, Jeffrey E Barrick

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 2 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Interaction between mutation type and gene pleiotropy drives parallel evolution in the laboratory.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Pooled it
  2. Modeling environmentally mediated rotavirus transmission: The role of temperature and hydrologic factors.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Pooled it
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  8. Evolution under vancomycin selection drives divergent collateral sensitivity patterns inProceedings of the National Academy of Sciences of the United States of America · 2025
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  9. Review
  10. Limited Diversity of Thermal Adaptation to a Critical Temperature inInternational journal of molecular sciences · 2025
    Article
  11. Review
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  14. Evolution of pH-sensitive transcription termination inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  18. Article
  19. Experimental Evolution in a Warming World: The Omics Era.Molecular biology and evolution · 2024
    Review
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Daniel E DeatherageCenter for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX 78712.
Jamie L KepnerCenter for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX 78712.
Albert F BennettDepartment of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697.
Richard E LenskiBEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, MI 48824; jbarrick@cm.utexas.edu lenski@msu.edu.
Jeffrey E BarrickCenter for Systems and Synthetic Biology, The University of Texas at Austin, Austin, TX 78712; jbarrick@cm.utexas.edu lenski@msu.edu.
Michigan State University · USThe University of Texas at Austin · USUniversity of California, Irvine · US

Funding

Identifying Mutations that Promote Microbial EvolvabilityR00GM087550 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI BARRICK, JEFFREY EVAN · 2011 to 2013
$724k
NIGMS NIH HHS R00 GM087550
6 · The paper itself

Abstract

Isolated populations derived from a common ancestor are expected to diverge genetically and phenotypically as they adapt to different local environments. To examine this process, 30 populations of

Indexed as

Directed Molecular EvolutionGenetic FitnessSelection, GeneticAdaptation, PhysiologicalEscherichia coliGenome, BacterialMutationPhenotypeTemperatureexperimental evolutiongenome evolutionmutationnatural selectiontemperature

Identifiers

PMID28202733
PMCPMC5347587
OpenAlexW2588469583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.