Evidence map›Paper›PMID 28202685›Full record

ArticleBiology letters2017

Paternal diet affects differential gene expression, but not sperm competition, in sons.

Felix Zajitschek, Susanne Zajitschek, Mollie Manier

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Biology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 24 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 3 countries.

Felix ZajitschekDepartment of Biological Sciences, George Washington University, Washington, DC, USA.ORCID 0000-0001-6010-6112
Susanne ZajitschekDepartment of Biological Sciences, George Washington University, Washington, DC, USA.ORCID 0000-0003-4676-9950
Mollie ManierDepartment of Biological Sciences, George Washington University, Washington, DC, USA manier@gwu.edu.ORCID 0000-0001-9114-8649
George Washington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parental environment can widely influence offspring phenotype, but paternal effects in the absence of parental care remain poorly understood. We asked if protein content in the larval diet of fathers affected paternity success and gene expression in their sons. We found that males reared on high-protein diet had sons that fared better during sperm competition, suggesting that postcopulatory sexual selection is subject to transgenerational paternal effects. Moreover, immune response genes were downregulated in sons of low-protein fathers, while genes involved in metabolic and reproductive processes were upregulated.

Indexed as

Dietary ProteinsAnimal Nutritional Physiological PhenomenaAnimalsDrosophila melanogasterFemaleLarvaMaleSequence Analysis, RNASpermatozoaDietary Proteinsgene expressionparental effectspostcopulatory sexual selectionRNAseqtranscriptomicstransgenerational effects

Identifiers

PMID28202685
PMCPMC5326516
OpenAlexW2587807512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.