Evidence map›Paper›PMID 28202646›Full record

ReviewThe Journal of experimental biology2017

Mussel adhesion - essential footwork.

J Herbert Waite

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of experimental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 182 papers.

0numbers the graph read from it
0cells of the map it votes in
182citing papers in PubMed
24.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

182 citing papers in PubMed, 640 citations in OpenAlex.

  1. Article
  2. Coacervates as bio-inspired intermediates for materials processing.Chemical communications (Cambridge, England) · 2026
    Review
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  14. Investigating byssus self-assembly ofMarine life science & technology · 2026
    Article
  15. Article
  16. Article
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  18. Identification and characterization of a wet adhesive protein extracted fromProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Review
  20. Article

122 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

J Herbert WaiteMarine Sciences Institute, University of California-Santa Barbara, Santa Barbara, CA 93106, USA waite@lifesci.ucsb.edu.ORCID 0000-0003-4683-7386
University of California, Santa Barbara · US

Funding

Translating Mussel AdhesionR01DE018468 · NIDCR · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI WAITE, JOHN HERBERT · 2008 to 2017
$4.2M
NIDCR NIH HHS R01 DE018468
6 · The paper itself

Abstract

Robust adhesion to wet, salt-encrusted, corroded and slimy surfaces has been an essential adaptation in the life histories of sessile marine organisms for hundreds of millions of years, but it remains a major impasse for technology. Mussel adhesion has served as one of many model systems providing a fundamental understanding of what is required for attachment to wet surfaces. Most polymer engineers have focused on the use of 3,4-dihydroxyphenyl-l-alanine (Dopa), a peculiar but abundant catecholic amino acid in mussel adhesive proteins. The premise of this Review is that although Dopa does have the potential for diverse cohesive and adhesive interactions, these will be difficult to achieve in synthetic homologs without a deeper knowledge of mussel biology; that is, how, at different length and time scales, mussels regulate the reactivity of their adhesive proteins. To deposit adhesive proteins onto target surfaces, the mussel foot creates an insulated reaction chamber with extreme reaction conditions such as low pH, low ionic strength and high reducing poise. These conditions enable adhesive proteins to undergo controlled fluid-fluid phase separation, surface adsorption and spreading, microstructure formation and, finally, solidification.

Indexed as

AdhesivenessAdhesivesAmino Acid SequenceAnimalsBivalviaDihydroxyphenylalanineHydrogen-Ion ConcentrationOsmolar ConcentrationProteinsTensile StrengthWettabilityadhesive protein, musselAdhesivesDihydroxyphenylalanineProteinsDopaFoot behaviorInterfacial chemistryMussel foot proteins

Identifiers

PMID28202646
PMCPMC5312731
OpenAlexW2587914684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.