ArticleJournal of immunology (Baltimore, Md. : 1950)2017
DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia.
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 41 citations in OpenAlex.
- Role of PTK6 in the diagnosis, prognosis, and immune infiltration of pancreatic cancer based on evidence from bioinformatics analysis and experimental validation.Discover oncology · 2026Article
- 8-Oxoguanine: A Lesion, an Epigenetic Mark, or a Molecular Signal?International journal of molecular sciences · 2025Review
- Unveiling the vital role of OGG1 in inflammation, vascular endothelial damage, and cell death in obstetric and gynecological diseases.Human cell · 2025Review
- Dysregulation of autophagy during photoaging reduce oxidative stress and inflammatory damage caused by UV.Frontiers in pharmacology · 2025Review
- Experimental animal models of acute respiratory distress syndrome: one-hit and two-hit establishment application.Frontiers in immunology · 2025Review
- OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy.Cell proliferation · 2023Article
- NLRX1 knockdown attenuates pro-apoptotic signaling and cell death in pulmonary hyperoxic acute injury.Scientific reports · 2023Article
- Molecular Mechanisms of Hyperoxia-Induced Neonatal Intestinal Injury.International journal of molecular sciences · 2023Review
- Hyperoxia in the management of respiratory failure: A literature review.Annals of medicine and surgery (2012) · 2022Review
- OGG1 in Lung-More than Base Excision Repair.Antioxidants (Basel, Switzerland) · 2022Review
- 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Exacerbates Doxorubicin-Induced Cardiac Dysfunction.Oxidative medicine and cellular longevity · 2022Article
- OGG1 in the Kidney: Beyond Base Excision Repair.Oxidative medicine and cellular longevity · 2022Review
- Autophagy, TERT, and mitochondrial dysfunction in hyperoxia.American journal of physiology. Heart and circulatory physiology · 2021Article
- Constitutive transgenic α-Klotho overexpression enhances resilience to and recovery from murine acute lung injury.American journal of physiology. Lung cellular and molecular physiology · 2021Article
- Crosstalk between autophagy and DNA repair systems.Turkish journal of biology = Turk biyoloji dergisi · 2021Article
- Pleiotropic roles of late embryogenesis abundant proteins ofComputational and structural biotechnology journal · 2021Review
- Hyperoxia and Lungs: What We Have Learned From Animal Models.Frontiers in medicine · 2021Review
- Autophagy Roles in Genome Maintenance.Cancers · 2020Review
- Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis.American journal of physiology. Lung cellular and molecular physiology · 2020Article
- Inhibitors of DNA Glycosylases as Prospective Drugs.International journal of molecular sciences · 2020Review
Corrections and comments
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
13 authors at 7 institutions in 3 countries.
Yan YeDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.
Ping LinDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.
Weidong ZhangDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.ORCID 0000-0003-2941-4285
Shirui TanDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.ORCID 0000-0001-6740-880X
Xikun ZhouDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.ORCID 0000-0001-6768-2382
Rongpeng LiDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.
Qinqin PuDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.
Jonathan L KoffDepartment of Medicine, Yale University, New Haven, CT 06510.
Archana DhasarathyDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203.
Feng MaInstitute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu 100005, People's Republic of China; and mafeng@hotmail.co.jp hellojjx@126.com xindeng@cityu.edu.hk.ORCID 0000-0002-1594-6064
Xin DengDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong 999077, People's Republic of China mafeng@hotmail.co.jp hellojjx@126.com xindeng@cityu.edu.hk.
Jianxin JiangState Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, The Third Military Medical University, Chongqing 400042, People's Republic of China; mafeng@hotmail.co.jp hellojjx@126.com xindeng@cityu.edu.hk.
Min WuDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND 58203; mafeng@hotmail.co.jp hellojjx@126.com xindeng@cityu.edu.hk.
University of North Dakota · USArmy Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNCity University of Hong Kong · HKJiangsu Normal University · CNSichuan University · CNYale University · US
Funding
Research CoresP20GM103442 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI Chris Jurgens · 2012 to 2026
$53.0MYersina perstis interactions with macrophagesP20GM113123 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BRADLEY, DAVID S. · 2016 to 2025
$19.9MPilot Projects CoreP30GM103329 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI GEIGER, JONATHAN DAVID · 2012 to 2016
$5.1MNovel Role of EGFR in Virus-Induced Asthma ExacerbationsR01HL125897 · NHLBI · YALE UNIVERSITY · PI KOFF, JONATHAN · 2015 to 2019
$2.1MLung innate immunity against bacterial infectionR01AI109317 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI WU, MIN · 2014 to 2018
$1.7MLung epithelium collaborates with alveolar macrophages in host defenseR15AI101973 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI WU, MIN · 2012 to 2012
$414kCeramide membrane microdomains regulate cytokine secretionR03AI097532 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI SINGH, BRIJ B · 2012 to 2013
$138kDNA Based Repair and MAP kinasesR03ES014690 · NIEHS · UNIVERSITY OF NORTH DAKOTA · PI WU, MIN · 2006 to 2007
$138kNHLBI NIH HHS R01 HL125897NIAID NIH HHS R01 AI109317NIAID NIH HHS R03 AI097532NIAID NIH HHS R15 AI101973NIEHS NIH HHS R03 ES014690NIGMS NIH HHS P20 GM103442NIGMS NIH HHS P20 GM113123NIGMS NIH HHS P30 GM103329
Abstract
Oxygen is supplied as a supportive treatment for patients suffering from acute respiratory distress syndrome. Unfortunately, high oxygen concentration increases reactive oxygen species generation, which causes DNA damage and ultimately cell death in the lung. Although 8-oxoguanine-DNA glycosylase (OGG-1) is involved in repairing hyperoxia-mediated DNA damage, the underlying molecular mechanism remains elusive. In this study, we report that
Indexed as
AutophagyDNA RepairAcute Lung InjuryAnimalsBlotting, WesternChromatin ImmunoprecipitationComet AssayCytokinesDisease Models, AnimalDNA GlycosylasesHyperoxiaImmunoprecipitationInflammationLungMiceMice, Inbred C57BLCytokinesDNA GlycosylasesOgg1 protein, mouse
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.