ArticleJournal of neurophysiology2017
Action potentials and ion conductances in wild-type and CALHM1-knockout type II taste cells.
Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Biology, function and structure of the calcium homeostasis modulator family.The Journal of physiology · 2025Review
- Effects of temperature on action potentials and ion conductances in type II taste-bud cells.American journal of physiology. Cell physiology · 2023Article
- Molecular logic of salt taste reception in special reference to transmembrane channel-like 4 (TMC4).The journal of physiological sciences : JPS · 2022Review
- TMC4 is a novel chloride channel involved in high-concentration salt taste sensation.The journal of physiological sciences : JPS · 2021Article
- Taste transduction and channel synapses in taste buds.Pflugers Archiv : European journal of physiology · 2021Review
- Peripheral and central mechanisms of cough hypersensitivity.Journal of thoracic disease · 2020Review
- Cell-type-independent expression of inwardly rectifying potassium currents in mouse fungiform taste bud cells.Physiological research · 2020Article
- Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.Science advances · 2020Article
- Article
- Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex.Science signaling · 2018Article
- CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.Neuron · 2018Article
- ATP Release Channels.International journal of molecular sciences · 2018Review
- Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening.Molecular cell · 2017Article
- The NHAmerican journal of physiology. Cell physiology · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Taste bud type II cells fire action potentials in response to tastants, triggering nonvesicular ATP release to gustatory neurons via voltage-gated CALHM1-associated ion channels. Whereas CALHM1 regulates mouse cortical neuron excitability, its roles in regulating type II cell excitability are unknown. In this study, we compared membrane conductances and action potentials in single identified TRPM5-GFP-expressing circumvallate papillae type II cells acutely isolated from wild-type (WT) and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.