Evidence map›Paper›PMID 28202543›Full record

ArticleThe Journal of biological chemistry2017

Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair.

Nicholas L Adkins, Sarah G Swygert, Parminder Kaur, Hengyao Niu, Sergei A Grigoryev, Patrick Sung, Hong Wang, Craig L Peterson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Generation of Recombinant Nucleosomes Containing Site-Specific DNA Damage.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  8. Review
  9. DNA end resection during homologous recombination.Current opinion in genetics & development · 2021
    Review
  10. R-Loops and Its Chro-Mates: The Strange Case of Dr. Jekyll and Mr. Hyde.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Dynamic human MutSα-MutLα complexes compact mismatched DNA.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nicholas L AdkinsFrom the Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Sarah G SwygertFrom the Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Parminder Kaurthe Department of Physics.
Hengyao Niuthe Department Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, and.
Sergei A Grigoryevthe Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
Patrick Sungthe Department Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520, and.
Hong Wangthe Department of Physics.
Craig L PetersonFrom the Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, craig.peterson@umassmed.edu.
University of Massachusetts Chan Medical School · USNorth Carolina State University · USYale University · USPennsylvania State University · US

Funding

Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Fred A. Wright · 2015 to 2026
$18.3M
YEAST DNA REPAIR GENES AND PROTEINS OF THE RAD52 GROUPR01ES007061 · NIEHS · YALE UNIVERSITY · PI Patrick Sung · 1995 to 2026
$9.4M
Regulation of chromatin dynamicsR35GM122519 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Craig L Peterson · 2017 to 2026
$9.2M
YEAST CHROMATIN STRUCTURE/FUNCTIONR01GM054096 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PETERSON, CRAIG L · 1997 to 2017
$5.7M
Mechanism of protein-mediated looping in a complex environmentR01GM107559 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI RIEHN, ROBERT, WANG, HONG · 2014 to 2017
$1.3M
Role of Chromatin and ATP-dependent Remodeling on DNA DSB ProcessingF32GM096701 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ADKINS, NICHOLAS LEONARD · 2011 to 2012
$90k
NIEHS NIH HHS P30 ES025128NIEHS NIH HHS R01 ES007061NIGMS NIH HHS F32 GM096701NIGMS NIH HHS R01 GM054096NIGMS NIH HHS R01 GM107559NIGMS NIH HHS R35 GM122519
6 · The paper itself

Abstract

Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity. When DSBs are repaired by homologous recombination, DNA ends can undergo extensive processing, producing long stretches of single-stranded DNA (ssDNA).

Indexed as

Chromatin Assembly and DisassemblyDNA Breaks, Double-StrandedDNA RepairDNA, Single-StrandedGenomic InstabilityHistonesNucleosomesProtein Processing, Post-TranslationalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsDNA, Single-StrandedFUN30 protein, S cerevisiaeHistonesNucleosomesSaccharomyces cerevisiae ProteinsTranscription Factorsanalytical ultracentrifugationatomic force microscopy (AFM)chromatin remodelingDNA repairDSB processingnucleosomessDNA

Identifiers

PMID28202543
PMCPMC5392674
OpenAlexW2587980633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.