Evidence map›Paper›PMID 28202500›Full record

Trial reportBMJ open2017

CanWalk: a feasibility study with embedded randomised controlled trial pilot of a walking intervention for people with recurrent or metastatic cancer.

Vicki Tsianakas, Jenny Harris, Emma Ream, Mieke Van Hemelrijck, Arnie Purushotham, Lorelei Mucci, James S A Green, Jacquetta Fewster, Jo Armes

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  11. Changes in physical activity since cancer diagnosis and associations with health-related quality of life: a study of adults living with advanced cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  12. Living With and Beyond Cancer With Comorbid Conditions: Qualitative Insights to Understand Psychosocial Support Needs.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
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  14. Review
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  19. Health behaviors and well-being among those "living" with metastatic cancer in Alabama.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Vicki TsianakasFlorence Nightingale Faculty of Nursing and Midwifery, Kings College London, Kings Health Partners, London, UK.
Jenny HarrisFlorence Nightingale Faculty of Nursing and Midwifery, Kings College London, Kings Health Partners, London, UK.ORCID 0000-0001-8933-117X
Emma ReamFaculty of Health and Medical Sciences, University of Surrey, School of Health Sciences, Guildford, UK.
Mieke Van HemelrijckDivision of Cancer Studies, Cancer Epidemiology Group, King's College London, Kings Health Partners, London, UK.
Arnie PurushothamDivision of Cancer Studies, Cancer Epidemiology Group, King's College London, Guys Hospital, UK.
Lorelei MucciDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA.
James S A GreenDepartment of Urology, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK.
Jacquetta FewsterWellbeing and Support Department, Macmillan Cancer Support, Physical Activity Team, London, UK.
Jo ArmesFlorence Nightingale Faculty of Nursing and Midwifery, Kings College London, Kings Health Partners, London, UK.
King's College London · GBBarts Health NHS Trust · GBGuy's Hospital · GBHarvard University · USMacmillan Cancer Support · GBUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWalking is an adaptable, inexpensive and accessible form of physical activity. However, its impact on quality of life (QoL) and symptom severity in people with advanced cancer is unknown. This study aimed to assess the feasibility and acceptability of a randomised controlled trial (RCT) of a community-based walking intervention to enhance QoL in people with recurrent/metastatic cancer.

designWe used a mixed-methods design comprising a 2-centre RCT and nested qualitative interviews.

participantsPatients with advanced breast, prostate, gynaecological or haematological cancers randomised 1:1 between intervention and usual care.

interventionThe intervention comprised Macmillan's 'Move More' information, a short motivational interview with a recommendation to walk for at least 30 min on alternate days and attend a volunteer-led group walk weekly. OUTCOMES: We assessed feasibility and acceptability of the intervention

resultsWe recruited 42 (38%) eligible participants. Recruitment was lower than anticipated (goal n=60), the most commonly reported reason being unable to commit to walking groups (n=19). Randomisation procedures worked well with groups evenly matched for age, sex and activity. By week 24, there was a 45% attrition rate. Most PROMs while acceptable were not sensitive to change and did not capture key benefits.

conclusionsThe intervention was acceptable, well tolerated and the study design was judged acceptable and feasible. Results are encouraging and demonstrate that exercise was popular and conveyed benefit to participants. Consequently, an effectiveness RCT is warranted, with some modifications to the intervention to include greater tailoring and more appropriate PROMs selected. TRIAL REGISTRATION NUMBER: ISRCTN42072606.

Indexed as

Patient ComplianceQuality of LifeWalkingAdultAffectAgedAged, 80 and overBreast NeoplasmsFatigueFeasibility StudiesFemaleGenital Neoplasms, FemaleHematologic NeoplasmsHumansInterviews as TopicMalefeasibility studiesmetastatic and recurrent cancerquality of liferandomised controlled trialwalking

Identifiers

PMID28202500
PMCPMC5318561
OpenAlexW2587904438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.