Trial reportBMC cardiovascular disorders2017
Variability of radiation doses of cardiac diagnostic imaging tests: the RADIO-EVINCI study (RADIationdOse subproject of the EVINCI study).
Trial report in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00979199 (Evaluation of Integrated Cardiac Imaging for the Detection and Characterization of Ischemic Heart Disease), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Integrated Cardiac Imaging for the Detection and Characterization of Ischemic Heart Disease
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Pooled it
- Comparing machine learning models and traditional approaches for predicting obstructive coronary artery disease: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- Cumulative radiation doses due to nuclear medicine examinations: a systematic review.The British journal of radiology · 2021Pooled it
- Patient radiation exposure during invasive graft surveillance after heart transplantation.Open heart · 2026Article
- Article
- Current and Emerging Approaches for Primary Prevention of Coronary Artery Disease Using Cardiac Computed Tomography.Current cardiology reports · 2024Review
- Influence of Body Mass Index on Radiation Exposure Across Imaging Modalities in the Evaluation of Chest Pain.Journal of the American Heart Association · 2024Article
- Investigating the Influence of High-Speed Gantry Rotation in Cardiac CT on Motion Artifacts in Aortic Stenosis Patients Not Premedicated with β-Blockers: The FAST-CCT Randomized Trial Protocol.Journal of cardiovascular development and disease · 2023Article
- Health Technology Assessment for In Silico Medicine: Social, Ethical and Legal Aspects.International journal of environmental research and public health · 2022Review
- Coronary Flow and Reserve by Enhanced Transthoracic Doppler Trumps Coronary Anatomy by Computed Tomography in Assessing Coronary Artery Stenosis.Diagnostics (Basel, Switzerland) · 2021Article
- The sub-millisievert era in CTCA: the technical basis of the new radiation dose approach.La Radiologia medica · 2020Review
- How Do PET Myocardial Blood Flow Reserve and FFR Differ?Current cardiology reports · 2020Review
- Hybrid anatomo-functional imaging of coronary artery disease: Beneficial irrespective of its core components.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
- Using radiation safely in cardiology: what imagers need to know.Heart (British Cardiac Society) · 2019Article
- TheNPJ digital medicine · 2019Review
- The new clinical standard of integrated quadruple stress echocardiography with ABCD protocol.Cardiovascular ultrasound · 2018Review
- Myocardial Assessment with Cardiac CT: Ischemic Heart Disease and Beyond.Current cardiovascular imaging reports · 2018Review
- Current status of stress myocardial perfusion imaging pharmaceuticals and radiation exposure in Japan: Results from a nationwide survey.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Efficacy of noninvasive cardiac imaging tests in diagnosis and management of stable coronary artery disease.Vascular health and risk management · 2017Review
- Optimizing the diagnosis and assessment of chronic thromboembolic pulmonary hypertension with advancing imaging modalities.Pulmonary circulationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with coronary artery disease can accumulate significant radiation dose through repeated exposures to coronary computed tomographic angiography, myocardial perfusion imaging with single photon emission computed tomography or positron emission tomography, and to invasive coronary angiography. Aim of the study was to audit radiation doses of coronary computed tomographic angiography, single photon emission computed tomography, positron emission tomography and invasive coronary angiography in patients enrolled in the prospective, randomized, multi-centre European study-EVINCI (Evaluation of Integrated Cardiac Imaging for the Detection and Characterization of Ischemic Heart Disease).
methodsWe reviewed 1070 tests (476 coronary computed tomographic angiographies, 85 positron emission tomographies, 310 single photon emission computed tomographies, 199 invasive coronary angiographies) performed in 476 patients (mean age 60 ± 9 years, 60% males) enrolled in 12 centers of the EVINCI. The effective doses were calculated in milli-Sievert (mSv) as median, interquartile range (IQR) and coefficient of variation of the mean.
resultsCoronary computed tomographic angiography (476 exams in 12 centers) median effective dose was 9.6 mSv (IQR = 13.2 mSv); single photon emission computed tomography (310 exams in 9 centers) effective dose was 9.3 (IQR = 2.8); positron emission tomography (85 in 3 centers) effective dose 1.8 (IQR = 1.6) and invasive coronary angiography (199 in 9 centers) effective dose 7.4 (IQR = 7.3). Inter-institutional variability was highest for invasive coronary angiography (100%) and coronary computed tomographic angiography (54%) and lowest for single photon emission computed tomography (20%). Intra-institutional variability was highest for invasive coronary angiography (121%) and coronary computed tomographic angiography (115%) and lowest for single photon emission computed tomography (14%).
conclusionCoronary computed tomographic angiography and invasive coronary angiography doses vary substantially between and within centers. The variability in nuclear medicine procedures is substantially lower. The findings highlight the need to audit doses, to track cumulative exposures and to standardize doses for imaging techniques.
trial registrationThe study protocol is available at https://www.clinicaltrials.gov/ (ClinicalTrials.gov Identifier: NCT00979199 ). Information provided on September 16, 2009.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.