MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats.

Kelsey C Patterson, Virginia E Hawkins, Kara M Arps, Daniel K Mulkey, Michelle L Olsen

Abstract readPublished Erratum

In one paragraph

Article in Human molecular genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes.Journal of biomedical science · 2020
Review
Cerebral organoids as tools to identify the developmental roots of autism.Molecular autism · 2020
Review
The Application of Adeno-Associated Viral Vector Gene Therapy to the Treatment of Fragile X Syndrome.Brain sciences · 2019
Review
Rett syndrome from bench to bedside: recent advances.F1000Research · 2018
Review
Current Perspectives in Autism Spectrum Disorder: From Genes to Therapy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
Review

4 · The record

Corrections and comments

Erratum for
MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats.2016

5 · Who and what money

Authors and funding

5 authors.

Kelsey C PattersonDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA.

Virginia E HawkinsDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.

Kara M ArpsDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA.

Daniel K MulkeyDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT, USA.

Michelle L OlsenDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

UAB Neuroscience Core CenterP30NS047466 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STANDAERT, DAVID G. · 2005 to 2019

$8.5M

Glial chemosensitivity: pH sensing and interactions with neuronal chemoreceptorsR01HL104101 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K, OLSEN, MICHELLE L · 2010 to 2024

$5.5M

NHLBI NIH HHS R01 HL104101NINDS NIH HHS P30 NS047466

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID28201743

DOI10.1093/hmg/ddw435

PMCPMC5953509

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.