Evidence map›Paper›PMID 28198885›Full record

ArticleOptics letters2017

Flexible, high-resolution micro-optical coherence tomography endobronchial probe toward in vivo imaging of cilia.

Dongyao Cui, Kengyeh K Chu, Biwei Yin, Timothy N Ford, Chulho Hyun, Hui Min Leung, Joseph A Gardecki, George M Solomon, Susan E Birket, Linbo Liu and 2 more

Abstract read
In one paragraph

Article in Optics letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Journal of biomedical optics · 2025
    Article
  3. Optical Imaging of Cilia in the Head and Neck.Journal of clinical medicine · 2025
    Review
  4. Article
  5. Optica · 2023
    Article
  6. Review
  7. Phase-resolved dynamic wavefront imaging of cilia metachronal waves.Quantitative imaging in medicine and surgery · 2023
    Article
  8. Article
  9. Extended depth of focus by self-imaging wavefront division with the mirror tunnel.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dongyao Cui
Kengyeh K Chu
Biwei Yin
Timothy N Ford
Chulho Hyun
Hui Min Leung
Joseph A Gardecki
George M Solomon
Susan E Birket
Linbo Liu
Steven M Rowe
Guillermo J Tearney

Funding

UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMIT GAGGAR · 2007 to 2026
$23.0M
Translational Program in CFTR-Related Airway DiseasesR35HL135816 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROWE, STEVEN MARK · 2017 to 2022
$6.3M
Functional Anatomic Imaging of CF Patients with Early Lung Disease Using microOCTR01HL116213 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROWE, STEVEN MARK, TEARNEY, GUILLERMO J · 2012 to 2015
$2.0M
The Mechanisms Underlying Abnormal Mucus and its Clearance in the Cystic Fibrosis RatK08HL131867 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BIRKET, SUSAN ELIZABETH · 2017 to 2021
$637k
NHLBI NIH HHS K08 HL131867NHLBI NIH HHS R01 HL116213NHLBI NIH HHS R35 HL135816NIDDK NIH HHS P30 DK072482
6 · The paper itself

Abstract

We report the design and fabrication of a flexible, longitudinally scanning high-resolution micro-optical coherence tomography (μOCT) endobronchial probe, optimized for micro-anatomical imaging in airways. The 2.4 mm diameter and flexibility of the probe allows it to be inserted into the instrument channel of a standard bronchoscope, enabling real-time video guidance of probe placement. To generate a depth-of-focus enhancing annular beam, we utilized a new fabrication method, whereby a hollow glass ferrule was angle-polished and gold-coated to produce an elongated annular reflector. We present validation data that verifies the preservation of linear scanning, despite the use of flexible materials. When utilized on excised, cultured mouse trachea, the probe acquired images of comparable quality to those obtained by a benchtop μOCT system.

Indexed as

Mechanical PhenomenaSignal-To-Noise RatioAnimalsBronchiCiliaEquipment DesignMiceTomography, Optical CoherenceTrachea

Identifiers

PMID28198885
PMCPMC5665567

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.