Evidence map›Paper›PMID 28198582›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Cation-Selective Channel Regulated by Anions According to Their Hofmeister Ranking.

Philip A Gurnev, Torri C Roark, Horia I Petrache, Alexander J Sodt, Sergey M Bezrukov

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Membrane protein-based biosensors.Journal of the Royal Society, Interface · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Philip A GurnevEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bldg. 9, Rm 1 N-124B, Bethesda, MD, 20892, USA.
Torri C RoarkEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bldg. 9, Rm 1 N-124B, Bethesda, MD, 20892, USA.
Horia I PetracheDepartment of Physics, Indiana University Purdue University Indianapolis, Indianapolis, IN, 46202, USA.
Alexander J SodtEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bldg. 9, Rm 1 N-124B, Bethesda, MD, 20892, USA.
Sergey M BezrukovEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bldg. 9, Rm 1 N-124B, Bethesda, MD, 20892, USA.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USIndiana University – Purdue University Indianapolis · US

Funding

Biophysics of Large Membrane ChannelsZIAHD000072 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BEZRUKOV, SERGEY M · 2009 to 2025
$22.8M
Molecular simulations of lipid curvature stress and its effect on transmembrane proteinsZIAHD008955 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SODT, ALEXANDER · 2016 to 2025
$6.2M
Biophysics of Large Membrane ChannelsZ01HD000072 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BEZRUKOV, SERGEY M · 2004 to 2008
$1.6M
Intramural NIH HHS Z01 HD000072
6 · The paper itself

Abstract

Specificity of small ions, the Hofmeister ranking, is long-known and has many applications including medicine. Yet it evades consistent theoretical description. Here we study the effect of Hofmeister anions on gramicidin A channels in lipid membranes. Counterintuitively, we find that conductance of this perfectly cation-selective channel increases about two-fold in the H

Indexed as

AnionsBacillusCationsGramicidinIon TransportKineticsLipid BilayersThermodynamicsUnilamellar LiposomesAnionsCationsGramicidinLipid BilayersUnilamellar Liposomesinterface phenomenaion channelsion specificitymembranesnanopores

Identifiers

PMID28198582
PMCPMC5518747
OpenAlexW2587851622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.