Evidence map›Paper›PMID 28198164›Full record

ArticleMaternal & child nutrition2017

Influence of maternal and socioeconomic factors on breast milk fatty acid composition in urban, low-income families.

Uma Nayak, Suman Kanungo, Dadong Zhang, E Ross Colgate, Marya P Carmolli, Ayan Dey, Masud Alam, Byomkesh Manna, Ranjan Kumar Nandy, Deok Ryun Kim and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Maternal & child nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The Effect of Cannabis Consumption During Lactation on the Macronutrient Concentrations in Breast Milk.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Are there paternal components in human milk?Sudanese journal of paediatrics · 2019
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 4 countries.

Uma NayakCenter for Public Health Genomics, University of Virginia, Charlottesville, 22908, Virginia, USA.
Suman KanungoNational Institute of Cholera and Enteric Diseases, Kolkata, India.
Dadong ZhangCenter for Public Health Genomics, University of Virginia, Charlottesville, 22908, Virginia, USA.
E Ross ColgateDepartment of Medicine and Vaccine Testing Center, University of Vermont College of Medicine, Burlington, Vermont, USA.
Marya P CarmolliDepartment of Medicine and Vaccine Testing Center, University of Vermont College of Medicine, Burlington, Vermont, USA.
Ayan DeyInternational Vaccine Institute, Seoul, South Korea.
Masud AlamInternational Center for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Byomkesh MannaNational Institute of Cholera and Enteric Diseases, Kolkata, India.
Ranjan Kumar NandyNational Institute of Cholera and Enteric Diseases, Kolkata, India.
Deok Ryun KimInternational Vaccine Institute, Seoul, South Korea.
Dilip Kumar PaulDr. B.C. Roy Post Graduate Institute of Paediatric Sciences, Kolkata, India.
Saugato ChoudhuryDr. B.C. Roy Post Graduate Institute of Paediatric Sciences, Kolkata, India.
Sushama SahooDr. B.C. Roy Post Graduate Institute of Paediatric Sciences, Kolkata, India.
William S HarrisOmegaQuant Analytics, Sioux Falls, South Dakota, USA.
Thomas F WierzbaInternational Vaccine Institute, Seoul, South Korea.
Tahmeed AhmedInternational Center for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Beth D KirkpatrickDepartment of Medicine and Vaccine Testing Center, University of Vermont College of Medicine, Burlington, Vermont, USA.
Rashidul HaqueInternational Center for Diarrhoeal Disease Research, Dhaka, Bangladesh.
William A PetriDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, 22908, Virginia, USA.
Josyf C MychaleckyjCenter for Public Health Genomics, University of Virginia, Charlottesville, 22908, Virginia, USA.ORCID 0000-0003-2595-0005
University of Virginia · USInstitute of Post Graduate Medical Education and Research · INInternational Centre for Diarrhoeal Disease Research · BDInternational Vaccine Institute · KRNational Institute of Cholera and Enteric Diseases · INUniversity of Vermont · US

Funding

FIELD STUDIES OF IMMUNITY TO AMEBIASIS IN BANGLADESHR01AI043596 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAROL A GILCHRIST, William A Petri · 1998 to 2026
$7.7M
6 · The paper itself

Abstract

The lipid composition of breast milk may have a significant impact on early infant growth and cognitive development. Comprehensive breast milk data is lacking from low-income populations in the Indian subcontinent impeding assessment of deficiencies and limiting development of maternal nutritional interventions. A single breast milk specimen was collected within 6 weeks postpartum from two low-income maternal cohorts of exclusively breastfed infants, from Dhaka, Bangladesh (n = 683) and Kolkata, India (n = 372) and assayed for percentage composition of 26 fatty acids. Mature milk (>15 days) in Dhaka (n = 99) compared to Kolkata (n = 372) was higher in total saturated fatty acid (SFA; mean 48% vs. 44%) and disproportionately lower in ω3-polyunsaturated fatty acid (PUFA), hence the ω6- and ω3-PUFA ratio in Dhaka were almost double the value in Kolkata. In both sites, after adjusting for days of lactation, increased maternal education was associated with decreased SFA and PUFA, and increasing birth order or total pregnancies was associated with decreasing ω6-PUFA or ω3-PUFA by a factor of 0.95 for each birth and pregnancy. In Dhaka, household prosperity was associated with decreased SFA and PUFA and increased ω6- and ω3-PUFA. Maternal height was associated with increased SFA and PUFA in Kolkata (1% increase per 1 cm), but body mass index showed no independent association with either ratio in either cohort. In summary, the socioeconomic factors of maternal education and household prosperity were associated with breast milk composition, although prosperity may only be important in higher cost of living communities. Associated maternal biological factors were height and infant birth order, but not adiposity. Further study is needed to elucidate the underlying mechanisms of these effects.

Indexed as

Socioeconomic FactorsUrban PopulationAdultBangladeshBody Mass IndexFatty Acids, Omega-3Fatty Acids, Omega-6FemaleHumansIndiaInfantLactationMilk, HumanPregnancyProspective StudiesYoung AdultFatty Acids, Omega-3Fatty Acids, Omega-6anthropometrybreast milkinfant growthlow-income countriespolyunsaturated fatty acidssocioeconomic factors

Identifiers

PMID28198164
PMCPMC5638057
OpenAlexW2588782256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.