Evidence map›Paper›PMID 28198101›Full record

SynthesisInternational wound journal2017

Systematic review and meta-analysis of the efficacy of epidermal grafting for wound healing.

Muholan Kanapathy, Oliver J Smith, Nadine Hachach-Haram, Nicola Bystrzonowski, Afshin Mosahebi, Toby Richards

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International wound journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muholan KanapathyDivision of Surgery & Interventional Science, University College London, London, UK.
Oliver J SmithLondon Wound Healing Group, Department of Plastic and Reconstructive Surgery, Royal Free NHS Foundation Trust Hospital, London, UK.
Nadine Hachach-HaramLondon Wound Healing Group, Department of Plastic and Reconstructive Surgery, Royal Free NHS Foundation Trust Hospital, London, UK.
Nicola BystrzonowskiLondon Wound Healing Group, Department of Plastic and Reconstructive Surgery, Royal Free NHS Foundation Trust Hospital, London, UK.
Afshin MosahebiDivision of Surgery & Interventional Science, University College London, London, UK.
Toby RichardsDivision of Surgery & Interventional Science, University College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous skin grafting is an important method for wound coverage; however, it is an invasive procedure and can cause donor site morbidity. Epidermal grafting (EG) enables epidermal transfer to wounds with minimal donor site morbidity. However, data to date have been heterogeneous. This study aims to synthesise the current evidence on EG for wound healing to establish the efficacy of this surgical technique. A comprehensive search in the MEDLINE, EMBASE and CENTRAL databases was conducted. The endpoints assessed were proportion of wounds healed and mean wound-healing time. This systematic review was conducted and reported according to the Meta-Analysis of Observational Studies in Epidemiology (MOOSE) guidelines. We identified 1568 articles, of which seven articles were included in this review - a total of 209 wounds in 190 patients. The mean wound duration was 17·06 weeks (95% CI 8·57-25·55). Of these, 71·5% (95% CI 56·7-84·2) of the wounds achieved complete healing. Mean time for complete wound healing was 5·53 weeks (95% CI 3·18-7·88). The mean donor site healing time was 7·48 days (95% CI 4·83-10·13), with no reported donor site morbidity. The current data are small and lack level 1 evidence.

Indexed as

EpidermisHumansSkin TransplantationTransplantation, AutologousWound HealingWounds and InjuriesEpidermal graftSkin graftSystematic reviewWound healing

Identifiers

PMID28198101
PMCPMC7950096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.