Evidence map›Paper›PMID 28197934›Full record

ArticleChinese journal of integrative medicine2017

Fuzheng Huayu Formula () prevents rat renal interstitial fibrosis induced by HgCl

Ji-Li Yuan, Yan-Yan Tao, Qing-Lan Wang, Li Shen, Cheng-Hai Liu

Abstract read
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In one paragraph

Article in Chinese journal of integrative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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  7. Evidence-based complementary and alternative medicine : eCAM · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ji-Li YuanInstitute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Yan-Yan TaoInstitute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Qing-Lan WangInstitute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Li ShenInstitute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Cheng-Hai LiuInstitute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. Chenghailiu@hotmail.com.
Shanghai University of Traditional Chinese Medicine · CNShuguang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the mechanism of action of Fuzheng Huayu Formula (, FZHY) against renal interstitial fibrosis (RIF) relating to oxidative injury and nuclear factor-kappa B (NF-κB) activity.

methodsThirty-two Sprague-Dawley rats were randomly divided into 3 groups: normal group, model group and FZHY treatment group. The RIF model was induced by oral administration of HgCl

resultsRenal interstitial fibrosis was induced by HgCl

conclusionsFZHY could protect kidney from oxidative injury intoxicated by HgCl

Indexed as

Down-RegulationOxidative StressAnimalsDrugs, Chinese HerbalFibrosisGlutathioneGlutathione PeroxidaseKidneyKidney DiseasesMaleMalondialdehydeMatrix Metalloproteinase 2Mercuric ChlorideModels, BiologicalNF-kappa BNF-KappaB Inhibitor alphaDrugs, Chinese Herbalfuzheng huayuGlutathioneGlutathione PeroxidaseMalondialdehydeMatrix Metalloproteinase 2Mercuric ChlorideNF-kappa BNF-KappaB Inhibitor alphaSuperoxide DismutaseTumor Necrosis Factor-alphaChinese medicineFuzheng Huayu Formulamatrix metalloproteinase-2mercuric chloridenuclear factor-kappa Boxidative stressrenal interstitial fifibrosistumor necrosis factor-α

Identifiers

PMID28197934
OpenAlexW2588446266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.