Evidence map›Paper›PMID 28197820›Full record

ArticleJapanese journal of radiology2017

Lung cancer screening with ultra-low dose CT using full iterative reconstruction.

Masayo Fujita, Toru Higaki, Yoshikazu Awaya, Toshio Nakanishi, Yuko Nakamura, Fuminari Tatsugami, Yasutaka Baba, Makoto Iida, Kazuo Awai

Abstract read
PubMed Publisher
In one paragraph

Article in Japanese journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Masayo FujitaDepartment of Diagnostic Radiology, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Toru HigakiDepartment of Diagnostic Radiology, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Yoshikazu AwayaDepartment of Internal Medicine, Miyoshi Central Hospital, 531 Sakaya-cho, Miyoshi, Hiroshima, 728-0023, Japan.
Toshio NakanishiDepartment of Internal Medicine, Miyoshi Central Hospital, 531 Sakaya-cho, Miyoshi, Hiroshima, 728-0023, Japan.
Yuko NakamuraDepartment of Diagnostic Radiology, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Fuminari TatsugamiDepartment of Diagnostic Radiology, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Yasutaka BabaDepartment of Diagnostic Radiology, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Makoto IidaDepartment of Diagnostic Radiology, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Kazuo AwaiDepartment of Diagnostic Radiology, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan. awai@hiroshima-u.ac.jp.ORCID http://orcid.org/0000-0002-5039-2546
Hiroshima University · JPMiyoshi Kasei (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the diagnostic capability of ultra-low-dose CT (ULDCT) with full iterative reconstruction (f-IR) for lung cancer screening. MATERIALS AND

methodsAll underwent ULDCT and/or low-dose CT (LD-CT) on a 320-detector scanner. ULDCT images were reconstructed with f-IR. We qualitatively and quantitatively studied 95 nodules in 69 subjects. Two radiologists classified the nodules on ULDCT images as solid-, part-solid-, and pure ground-glass (PGG) and recorded their mean size. Their findings were compared with the reference standard. The observer performance study included 7 other radiologists and 35 subjects with- and 15 without nodules. The results were analyzed by AFROC analysis.

resultsIn the qualitative study, the kappa values between observers 1 and 2, respectively, and the reference standard were 0.70 and 0.83; the intra-class correlation coefficients for the nodule diameter between the reference standard and their measurements were 0.84 and 0.90. The 95% confidence interval (CI) for the area under the curve (AUC) difference for nodule detection on LDCT and ULDCT was -0.03 to 0.07. The 95% CI crossed the 0 difference in the AUC but not the pre-defined non-inferiority margin of -0.08.

conclusionThe diagnostic ability of ULDCT using f-IR is comparable to LDCT.

Indexed as

AgedEarly Detection of CancerFemaleHumansLung NeoplasmsMaleMiddle AgedRadiation DosageRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedLow-dose CTLung cancer CT screeningUltra-low-dose CT

Identifiers

PMID28197820
OpenAlexW2587862888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.