Evidence map›Paper›PMID 28197764›Full record

ReviewInternational urology and nephrology2017

New frontiers in prostate cancer imaging: clinical utility of prostate-specific membrane antigen positron emission tomography.

Asim Afaq, Deepak Batura, Jamshed Bomanji

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Asim AfaqInstitute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, Euston Road, London, UK.
Deepak BaturaDepartment of Urology, London North West Healthcare NHS Trust, Watford Road, London, UK. deepakbatura@gmail.com.ORCID http://orcid.org/0000-0002-2833-1819
Jamshed BomanjiInstitute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, Euston Road, London, UK.
University College London Hospitals NHS Foundation Trust · GBLondon North West Healthcare NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate-specific membrane antigen positron emission tomography (PSMA PET) is a relatively new method of imaging prostate cancer that increases diagnostic accuracy in detecting and guiding management in various stages of the disease pathway. Gallium-68-labelled PSMA PET has increased the sensitivity of detection of disease recurrence at low PSA levels, thus allowing an optimal window for salvage treatment. Apart from its use in disease recurrence, PSMA PET has the potential for increasing sensitivity and specificity for primary tumour localisation and in detecting lymph node disease, leading to a more accurate initial staging of the condition. In advanced disease, the use of PSMA PET may be able to assess response to treatment and also guide treatment with radionuclide therapy. Newer ligands under development might provide avenues for theranostic or personalised therapy applications with early data showing high PSA response rates. The rate of translation of PSMA PET into clinical practice has been remarkable. The use of this modality is likely to increase with future efforts to modify the radiotracer including

Indexed as

Gallium RadioisotopesProstate-Specific AntigenAgedAged, 80 and overHumansMagnetic Resonance ImagingMaleMiddle AgedMultimodal ImagingNeoplasm InvasivenessNeoplasm StagingPositron-Emission TomographyProstatic NeoplasmsSensitivity and SpecificityUnited KingdomGallium-68Gallium RadioisotopesProstate-Specific AntigenImagingProstate cancerPSMA PETRadiotracersTheranostics

Identifiers

PMID28197764
OpenAlexW2588809929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.