Evidence map›Paper›PMID 28197551›Full record

ArticleeNeuro

EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.

Teng Teng, Afsaneh Gaillard, Aude Muzerelle, Patricia Gaspar

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Development of prefrontal cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  3. Article
  4. Article
  5. Developmental Disruption ofFrontiers in cell and developmental biology · 2021
    Article
  6. Article
  7. Serotonergic afferents from the dorsal raphe decrease the excitability of pyramidal neurons in the anterior piriform cortex.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Article
  9. Article
  10. Serotonin neuron development: shaping molecular and structural identities.Wiley interdisciplinary reviews. Developmental biology · 2018
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Teng TengInserm UMR-S 839, 75005, Paris, France; Université Pierre et Marie Curie, Paris, France; Institut du Fer à Moulin, Paris, France.ORCID 0000-0003-3701-0002
Afsaneh GaillardInserm 1084, Poitiers, France; Université de Poitiers, Poitiers, France.ORCID 0000-0002-9375-6506
Aude MuzerelleInserm UMR-S 839, 75005, Paris, France; Université Pierre et Marie Curie, Paris, France; Institut du Fer à Moulin, Paris, France.
Patricia GasparInserm UMR-S 839, 75005, Paris, France; Université Pierre et Marie Curie, Paris, France; Institut du Fer à Moulin, Paris, France.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serotonin (5-HT) neurotransmission in the brain relies on a widespread axon terminal network originating from the hindbrain raphe nuclei. These projections are topographically organized such that the dorsal (DR), and median raphe (MnR) nuclei have different brain targets. However, the guidance molecules involved in this selective targeting in development are unknown. Here, we show the implication of ephrinA5 signaling in this process. We find that the

Indexed as

Age FactorsAmygdalaAnimalsAnimals, NewbornCells, CulturedEmbryo, MammalianEphrin-A5EphrinsGene Expression Regulation, DevelopmentalGreen Fluorescent ProteinsMiceMice, TransgenicMidbrain Raphe NucleiNeural PathwaysProsencephalonSerotoninEphrin-A5EphrinsFev protein, mouseGreen Fluorescent ProteinsSerotoninSerotonin Plasma Membrane Transport ProteinsTph2 protein, mouseTranscription FactorsTryptophan HydroxylaseamygdalacultureEphrinhypothalamusin utero electroporationolfactory bulb

Identifiers

PMID28197551
PMCPMC5292598
OpenAlexW2580732764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.